Product ID:O-4525, SULFANILAMIDE
MSDS Date:05/18/1988
FSC:6810
NIIN:00N015831
MSDS Number: BPLBZ

FISHER SCIENTIFIC

1 REAGENT LANE
FAIR LAWN, NJ 07410-2802
US

Emergency Phone: 201-796-7100

Info Phone: 201-796-7100

Cage: 1B464

FISHER SCIENTIFIC CO. CHEMICAL MFG DIV

FAIRLAWN, NJ 07410-2802 US

Telephone: 201-796-7100

Cage: 1B464

PRESENCE OF SYMPS.) GIVE METHYLENE BLUE, 1% SOLN,

RTECS: 9999999ZZ

NOT AVAIL, GIVE ASCORBIC ACID, 1 GM SLOWLY IV.

RTECS: 9999999ZZ

ABOVE 40%. CONTINUE O*2 THERAPY FOR AT LEAST 2 HRS

RTECS: 9999999ZZ

BE GIVEN BY QUALIFIED MEDICAL PERSONNEL.

RTECS: 9999999ZZ

CYANOSIS. OTHER SYMPS MAY INCL CEREBRAL & GI EFTS

RTECS: 9999999ZZ

EVEN UNCON. TOX FEVER MAY DEVELOP ONE/MORE DAYS AFTER

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OF MORE SERIOUS MANIFESTATIONS OF POISONING, NAMELY

RTECS: 9999999ZZ

AGRANULOCYTIC ANGINA, DERM OR TOX NEURITIS. JAUNDICE

RTECS: 9999999ZZ

SYMPS SIMILAR TO ACUTE

RTECS: 9999999ZZ

FROM ORAL ADMINISTRATION FOR 1-22 DAYS IN PREGNANT

RTECS: 9999999ZZ

HAZARD AREA & DENY ENTRY. VENTILATE CLOSED

RTECS: 9999999ZZ

TO MAX RESP PROT. CHEM CARTRIDGE RESP W/ORG VAP

RTECS: 9999999ZZ

FULL FACEPIECE. HIGH-EFFICIENCY PARTICULATE RESP

RTECS: 9999999ZZ

EFFICIENCY FILTER W/FULL FACEPIECE. TYPE "C"

RTECS: 9999999ZZ

OR OTHER POS PRESS MODE OR W/FULL FACEPIECE, HELMET

RTECS: 9999999ZZ

FULL FACEPIECE OPERATED IN PRESSURE-DEMAND OR OTHER

RTECS: 9999999ZZ

IF VICTIM IS CONSCIOUS, IMMED GIVE

RTECS: 9999999ZZ

TO BACK OF THROAT. GET MD IMMED.

RTECS: 9999999ZZ

SULFANILAMIDE

CAS: 63-74-1

RTECS: WO8400000

Fraction By Weight: 100%

MACULOPAPULAR ERYTHEMATOUS SKIN ERUPTIONS,

RTECS: 9999999ZZ

REPORTED. SYSTEMIC EFTS FROM ORAL ADMIN MAY INCL

RTECS: 9999999ZZ

ASTIGMATISM, CONJUNCT & TEMPORARY IMPAIRMENT OF DEPTH

RTECS: 9999999ZZ

LD50 LC50 Mixture:LD50:(ORAL RAT) 10500 MG/KG
Routes of Entry: Inhalation:NO Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:SULFANILAMIDE IS A METHEMOGLOBIN
FORMER. POISONING MAY AFFECT LIVER/KIDNEYS. CONCURRENT ADMIN OF
VARIOUS DRUGS W/SULFANILAMIDE MAY CAUSE ADVERSE EFTS. TOPICAL OR
ORAL USE OF PARA-AMINOBENZOIC ACID ANT AGONIZED SULFONAMIDE EFT;
MARKEDLY INCRD ANTICOAGULANT EFTS W/ORAL ANTICOAGULANTS; POSS
ADDITIVE BONE (EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT.
Effects of Overexposure:HLTH HAZ:MARROW DEPRESS W/CHLORAMPHENICOL; POSS
INCR HYPOGLYCEMA EFT W/ORAL HYPOGLYCEMIAS; POSS ADDITIVE
HEPATOTOXICITY W/HEPATOTOXINS; ACIDIFIES THE URINE, INCR POSS OF
SULFONAMIDE CRYSTALLURIA W/MET HENAMINE; INCR IN SERUM
METHOTREXATEE LEVELS, POSS LEADING TO TOX W/METHOTREXATE; MAY INCR
HEPATIC METABOLISM (SUP DAT)
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:INHAL:MOVE TO FRESH AIR IMMED. IF BRTHG HAS STOPPED, PERFORM
ARTF RESP. KEEP PERS WARM/AT REST. GET MD IMMED. SKIN:REMOVE
CONTAMD CLTHG/SHOES IMMED. WASH AFFECTED AREA W/SOAP/MILD DETERGENT
& LGE AMTS OF WATER FOR AT LEAST 15-20 MINS UNTILNO CHEM REMAINS.
GET MD IMMED. EYES:WASH IMMED W/LGE AMTS OF WATER, OCCASNLY LIFTING
UPPER/LOWER LIDS, UNTIL NO CHEM REMAINS (15-20 MINS). GET MD
IMMED.(ING 17)

Flash Point:NON-FLAMMABLE
Extinguishing Media:USE DRY CHEMICAL, CO*2, HALON, WATER SPRAY OR
STANDARD FOAM. LARGER FIRES USE WATER SPARY, FOG OR STANDARD FOAM
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED SCBA & FULL
PROTECTIVE EQUIPMENT . NO ACUTE HAZARD. MOVE CONTR FROM FIRE AREA
IF POSS. AVOID BREATHING VAPORS/DUSTS. KEEP UPWIND.
Unusual Fire/Explosion Hazard:NEGLIGIBLE FIRE HAZARD WHEN EXPOSED TO
HEAT OR FLAME.

Spill Release Procedures:OCCUP SPILL:DO NOT TOUCH SPILLED MATL. STOP
LEAK IF YOU CAN W/OUT RISK. SMALL SPILL:TAKE UP W/SAND OR OTHER
ABSORB MATL & PLACE INTO CONTRS FOR LATER DISP. LGE SPILL:DIKE FAR
AHEAD OF SPILL FOR LATER DISP. KEEP UNNEC PEOPLE AWAY. ISOLATE
(ING 11)
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:NONE SPECIFIED BY MANUFACTURER.
Other Precautions:NONE SPECIFIED BY MANUFACTURER.

Respiratory Protection:SPECIFIC RESP SELECTED MUST BE BASED ON CONTAM
LEVELS FOUND IN WORK PLACE, MUST NOT EXCEED WORKING LIMITS OF RESP
& BE NIOSH/MSHA APPRVD. FOLLOWING RESPS ARE RECOM BASED ON DATA
FOUND IN MSDS. THEY AR E RANKED IN ORDER FROM MIN (ING 12)
Ventilation:PROVIDE LOCAL EXHAUST OR GENERAL DILUTION VENTILATION
SYSTEM.
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:WEAR APPROPRIATE PROTECTIVE (IMPERVIOUS)
CLTHG & EQUIP TO PREVENT RPTD/PRLNGD SKIN CONTACT W/THIS SUBSTANCE.
Work Hygienic Practices:CONTACT LENSES SHOULD NOT BE WORN.
Supplemental Safety and Health
PH:5.8-6.1 @ 0.5% SOLN. EFTS OF OVEREXP:OR DECR ABSORP OF ESTOGEN
W/ORAL CONTRACEPTIVES; INCR PHENYTOIN EFT, POSS LEADING TO TOX
W/PHENYOIN & OTHER HYDANTOINS; INCR THIOPENTAL LEVELS, POSS LEADING
TO TOX W/THIOPENTAL. ACUTE: INHAL:NO DATA AVAIL. SKIN:NO LOC EFTS
REPORTED. SYSTEMIC EFTS FROM ORAL ADMIN MAY INCL (ING 2)

HCC:N1
Melt/Freeze Pt:M.P/F.P Text:329F,165C
Spec Gravity:1.08
pH:SUPDAT
Solubility in Water:7.5%
Appearance and Odor:WHITE TO YELLOW POWDER.

Stability Indicator/Materials to Avoid:YES
NO DATA AVAILABLE.
Stability Condition to Avoid:NO DATA AVAILABLE.
Hazardous Decomposition Products:THERMAL DECOMPOSITION PRODUCTS INCLUDE
TOXIC OXIDES OF NITROGEN & SULFUR.

Waste Disposal Methods:DISPOSAL MUST BE IN ACCORDANCE W/FEDERAL, STATE
& LOCAL REGULATIONS .

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particular situation.