CGHVK - D H E 45 INJECTION

Product Identification

Product ID:D H E 45 INJECTION
MSDS Date:04/15/1993
FSC:6850
NIIN:00F054863
MSDS Number: CGHVK

Responsible Party
SANDOZ PHARMACEUTICALS - DIV OF SANDOZ INC
59 RT 10
EAST HANOVER, NJ 07936-1005
US

Emergency Phone: 201-503-7000/201-503-8223

Info Phone: 201-503-7000/201-503-8223

Cage: 04520

Contractor
NOVARTIS PHARMACEUTICALS CORP
EAST HANOVER, NJ 07936-1080 US

Telephone: 800-742-2422/973-781-5476

Cage: 04520

Ingredients

DIHYDROERGOTAMINE AMESYLATE *97-4*

CAS: 6190-39-2

RTECS: KE7920000


ETHANOL (ETHYL ALCOHOL), TECSOL, ALCOHOL, SYNASOL *97-4*

CAS: 64-17-5

RTECS: KQ6300000

Fraction By Weight: 6.1%/VOL

OSHA PEL 1000 PPM

ACGIH TLV: 1000 PPM


GLYCERINE, 1,2,3,-TRIHYDROXYPROPANE, GLYCEROL, ANHYDROUS

CAS: 56-81-5

RTECS: MA8050000

Fraction By Weight: 15%/WT

ACGIH TLV: 10 MG/CUM (VAPOR)

Hazards

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:D H E IS AN ALPHA ADRENERGIC BLOCKING
AGENT W/A STIMULATING EFFECT ON SMOOTH MUSCLE PERIPHERAL & CRANIAL
BLOOD VESSELS & PRODUCES DEPRESSION OF CENTRAL VASOMOTOR CENTERS.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:NUMBNESS & TINGLING OF FINGERS & TOES,
EXTREMITY MUSCLE PAINS, NAUSEA, VOMITING, LOCALIZED EDEMA & ITCHING
Medical Cond Aggravated by Exposure:PERIPHERAL VASCULAR DISEASE,
CORONARY HEART DISEASE, HYPERTENSION, IMPAIRED HEPATIC/RENAL
FUNCTION, SEPSIS, PREGNANCY

First Aid

First Aid:EYES/SKIN: FLUSH W/RUNNING WATER. OBTAIN MEDICAL ATTENTION IN
ALL CASES.

Fire Fighting

Extinguishing Media:AS APPROPRIATE FOR SURROUNDING FIRE & MATERIALS.
Fire Fighting Procedures:NONE
Unusual Fire/Explosion Hazard:NONE

Accidental Release

Spill Release Procedures:CONTAIN W/ABSORBENT MATERIAL & PLACE IN CLOSED
CONTAINER FOR DISPOSAL. VENTILATE AREA.

Handling

Handling and Storage Precautions:FOR PRODUCT INTEGRITY STORE BELOW 77F.
PROTECT FROM LIGHT. DON'T USE AMPUL SOLUTION IF DISCOLORED.
Other Precautions:NONE

Exposure Controls

Respiratory Protection:USE NIOSH APPROVED RESPIRATOR W/ORGANIC VAPOR
CARTRIDGE FOR SPILLS ONLY.
Ventilation:MECHANICAL (GENERAL): NORMAL ROOM EXHAUST.
Protective Gloves:REQUIRED
Eye Protection:GOGGLES
Other Protective Equipment:NONE
Work Hygienic Practices:NONE
Supplemental Safety and Health

Chemical Properties

Solubility in Water:SLIGHTLY
Appearance and Odor:CLEAR, COLORLESS SOLUTIONS IN AMPULS

Stability

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:CO, CO2, NITROGEN OXIDES & SULFUR
OXIDES

Disposal

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE W/LOCAL, STATE &
FEDERAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.