Product ID:CLEOCIN PHOSPHATE IV SOLUTION
MSDS Date:06/30/1994
FSC:6505
NIIN:01-185-3309
MSDS Number: BXJXX

UPJOHN COMPANY, THE

7171 PORTAGE ROAD
KALAMAZOO, MI 49001-0199
US

Emergency Phone: 616-323-5122 (24 HOURS)

Info Phone: 30 PM)

Cage: 93703

PHARMACIA & UPJOHN

KALAMAZOO, MI 49001-0199 US

Telephone: 616-833-5122/616-833-7555

Cage: 93703

WATER

CAS: 7732-18-5

RTECS: ZC0110000

Fraction By Weight: < 94% %

DEXTROSE

CAS: 50-99-7

RTECS: LZ6600000

Fraction By Weight: 5% %

CLINDAMYCIN PHOSPHATE

CAS: 24729-96-2

RTECS: GF2625000

Fraction By Weight: 0.6-1.8%

LD50 LC50 Mixture:LD50 (ORAL, RAT): 1,832 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:MAY CAUSE GASTROINTESTINAL EFFECTS,
SKIN RASH, REDNESS AND ITCHING, NEUTROPENIA, THROMBOCYTOPENIA,
ABNORMALITIES IN LIVER FUNCTION TESTS AND RENAL DYSFUNCTION, EYE
IRRITATION, SKIN IRRITATION AND IRRI TATION OF RESPIRATORY
PASSAGES.
Explanation of Carcinogenicity:THIS COMPOUND CONTAINS NO INGREDIENTS AT
CONCENTRATIONS OF 0.1% OR GREATER THAT ARE CARCINOGENS OR SUSPECT
CARCINOGENS.
Effects of Overexposure:NAUSEA, VOMITING, DIARRHES, ABDOMINAL PAIN,
PASSAGE OF MUCOUS AND BLOOD IN STOOLS, PSEUDOMEMBRANOUS COLITIS,
ESOPHAGITIS, SKIN RASH/REDNESS/ITCHING, SORE THROAT, FEVER, UNUSUAL
BLEEDING OR BRUISING, J AUNDICE, EYE IRRITATION, SKIN IRRITATION,
RESPIRATORY TRACT IRRITATION.
Medical Cond Aggravated by Exposure:CONTRAINDICATED IN PEOPLE WITH A
HISTORY OF HYPERSENSITIVITY TO CLINDAMYCIN, LINCOMYCIN OR OTHER
RELATED FAMILIES OF ANTIBIOTICS, A HISTORY OF ENTERITIS OR
ULCERATIVE COLITIS, ATOPY, HEPATIC DISEASE.

First Aid:GET MEDICAL ATTENTION IF SYMPTOMS PERSIST. EYE:FLUSH WITH
WATER FOR 15 MINUTES. HOLD EYELIDS OPEN. SKIN:WASH WITH SOAP &
WATER. INHALED:REMOVE TO FRESH AIR. ORAL:CONTACT A PHYSICIAN OR
POISON CONTROL CENTER.

Flash Point:NONFLAMMABLE
Lower Limits:NOT GIVEN
Upper Limits:NOT GIVEN
Extinguishing Media:WATER SPRAY, CARBON DIOXIDE OR DRY CHEMICAL.
Fire Fighting Procedures:WEAR PROTECTIVE CLOTHING AND NIOSH-APPROVED
SELF-CONTAINED BREATHING APPARATUS.
Unusual Fire/Explosion Hazard:NONE SPECIFIED BY MANUFACTURER.

Spill Release Procedures:SMALL AMOUNTS OF THE PRODUCT CAN BE DILUTED
WITH ALCOHOL AND WIPED UP. WEAR PROTECTIVE EQUIPMENTS. VENTILATE
AREA. KEEP OUT OF DRAINS AND WATERRWAYS. SMALL SPILLS SHOULD BE
ABSORBED WITH PAPER TOWEL OR OTHER APPROPRIATE MEDIA.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE IN COOL, DRY PLACE AWAY FROM
LIGHT. KEEP OUT OF REACH OF CHILDREN. LAUNDER CONTAMINATED CLOTHING
BEFORE REUSE.
Other Precautions:AVOID CONTACT WITH EYES AND SKIN. WASH THOROUGHLY
AFTER HANDLING MATERIAL.

Respiratory Protection:NONE NORMALLY REQUIRED.
Ventilation:LOCAL EXHAUST
Protective Gloves:RUBBER.
Eye Protection:SAFETY GLASSES WITH SIDE SHIELDS.
Other Protective Equipment:EYE WASH STATION, PROTECTIVE CLOTHING AND/OR
UNIFORM
Work Hygienic Practices:OBSERVE GOOD PERSONAL HYGIENE PRACTICES AND
RECOMMENDED PROCEDURES.
Supplemental Safety and Health
NONE SPECIFIED BY MANUFACTURER.

HCC:T6
Boiling Pt:B.P. Text:NOT GIVEN
Melt/Freeze Pt:M.P/F.P Text:NOT GIVEN
Decomp Temp:Decomp Text:NOT GIVEN
Vapor Pres:NOT GIVEN
Vapor Density:NOT GIVEN
Spec Gravity:NOT GIVEN
Evaporation Rate & Reference:NOT RELEVANT
Solubility in Water:SOLUBLE
Appearance and Odor:CLEAR LIQUID IN 50 ML BAG

Stability Indicator/Materials to Avoid:YES
NONE SPECIFIED BY MANUFACTURER.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:CARBON DIOXIDE, CARBON MONOXIDE,
CARBON DIOXIDE, SULFUR OXIDES, NITROGEN OXIDES.

Waste Disposal Methods:DISPOSE OF BY INCINERATION IN ACCORDANCE WITH
ALL LOCAL, STATE AND FEDERAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.