Product ID:PURINETHOL
MSDS Date:08/24/1988
FSC:6505
NIIN:01-149-3553
MSDS Number: BHJGT

Emergency Phone: 919-248-3000

Info Phone: 919-248-3000

Cage: 5P291

Cage: 5P291

MERCAPTOPURINE (50 MG ACTIVE INGREDIENT)

CAS: 6112-76-1

RTECS: UP0400000

LD50 LC50 Mixture:LD50 (ORAL MOUSE) IS 480 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:MOST CONSISTENT,DOSE-RELATED TOXICITY
IS BONE MARROW SUPPRESSION.THIS MAY CAUSE
ANEMIA,THROMBOCYTOPENIA,LEUKOPENIA OR ANY
COMBINATION.MERCAPTOPURINE IS HEPATOTOXIC,CAN CAUSE FETAL HARM,AND
CHROMOSOMAL ABERRATIONS.INDUCES DOMINANT-LETHAL MUTATIONS IN MALE
MICE.
Explanation of Carcinogenicity:MANUFACTURER STATES THAT MERCAPTOPURINE
IS A SUSPECTED HUMAN CARCINOGEN.
Effects of Overexposure:MANUFACTURER DID NOT SPECIFY.
Medical Cond Aggravated by Exposure:INDIVIDUALS WITH OF BLOOD AND LIVER
DISEASES,AND PREGNANT WOMEN SHOULD NOT BE EXPOSED TO THIS PRODUCT.

First Aid:EYES:RINSE IMMEDIATELY WITH PLENTY OF WATER.CONTACT
PHYSICIAN. SKIN:WASH SKIN OFF WITH PLENTY OF WATER.CONTACT
PHYSICIAN IF CONTACT IS PROLONGED. INGESTION:WASH OUT MOUTH.GIVE
PLENTY OF FLUIDS.CONTACT PHYSICIAN.

Extinguishing Media:USE CARBON DIOXIDE, FOAM, DRY CHEMICAL, OR WATER
FOG.
Fire Fighting Procedures:FIRE FIGHTERS SHOULD USE NIOSH APPROVED SCBA &
FULL PROTECTIVE EQUIPMENT WHEN FIGHTING CHEMICAL FIRE. USE WATER
SPRAY TO COOL NEARBY CONTAINERS EXPOSED TO FIRE.
Unusual Fire/Explosion Hazard:FIRE OR EXCESSIVE HEAT MAY CAUSE
PRODUCTION OF TOXIC OR IRRITANT FUMES.

Spill Release Procedures:WEAR SUITABLE PROTECTIVE EQUIPMENT AND
CLOTHING.SWEEP UP MINIMIZING DUST EVOLUTION.TRANSFER TO CLOSED
CONTAINER FOR DISPOSAL.DECONTAMINATE AREA WITH DILUTE ALKALINE
PERMANGANATE SOLUTION THEN WASH WIT H WATER.CLEAN AREA WITH
DETERGENT.
Neutralizing Agent:DILUTE ALKALINE PERMANGANATE SOLUTION.

Handling and Storage Precautions:KEEP IN ORIGINAL CONTAINER TIGHTLY
CLOSED. PROTECT FROM LIGHT.
Other Precautions:NONE.

Respiratory Protection:AIR SUPPLIED HOOD.
Ventilation:LOCAL EXHAUST OR BIOLOGICAL SAFETY CABINET.
Protective Gloves:RUBBER OR DOUBLE LATEX.
Eye Protection:CHEMICAL SAFETY GOGGLES
Other Protective Equipment:TYVEK JUMP SUIT.
Work Hygienic Practices:WASH THROUGHLY AFTER HANDLING AND BEFORE
EATING. LAUNDER CONTAMINATED CLOTHING BEFORE REUSE.
Supplemental Safety and Health
NONE.

HCC:T6
Melt/Freeze Pt:M.P/F.P Text:572F,DECOMP
Solubility in Water:APPRECIABLE.
Appearance and Odor:YELLOW,ODORLESS,ALMOST TASTELESS,CRYSTALLINE
POWDER.

Stability Indicator/Materials to Avoid:YES
NONE NOTED.
Stability Condition to Avoid:NONE.
Hazardous Decomposition Products:CARBON DIOXIDE, CARBON MONOXIDE,
INCOMPLETELY BURNED CARBON PRODUCTS.

Waste Disposal Methods:ARRANGE FOR CHEMICAL INCINERATION. WASH WATER
AND RINSES SHOULD BE DISCHARGED TO AN APPROVED SEWERAGE SYSTEM.
DISPOSE OF IN ACCORDANCE WITH ALL APPLICABLE FEDERAL, STATE AND
LOCAL LAWS AND REGULATIONS REGARDING DISPOSAL OF POTENT
MEDICINALWASTE.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.