Product ID:COLY-MYCIN S OTIC
MSDS Date:06/06/1991
FSC:6505
NIIN:00F034802
MSDS Number: BTKGF

PARK-DAVIS DIV OF WARNER LAMBERT LTD

201 TABOR ROAD
MORRIS PLAINS, NJ 07950-2614
US

Emergency Phone: 201-540-2000

Info Phone: 201-540-2000

Preparer: ROY MUELLER

Cage: 2T119

PARKE-DAVIS DIV OF WARNER-LAMBERT CO

DETROIT, MI 48232 US

Telephone: 201-540-2000

Cage: 91378

COLISTIN SULFATE

CAS: 1264-72-8

RTECS: TR1500000

NEOMYSIN SULFATE

CAS: 1405-10-3

RTECS: QP4375000

HYDROCORTISONE ACETATE

CAS: 50-03-3

RTECS: GM8960000

THONZONIUM BROMIDE(SURFACE-ACTIVE AGENT)

Fraction By Weight: 0.05%

LD50 LC50 Mixture:SEE SUPPLEMENTARY DATA FOR LD50'S
Routes of Entry: Inhalation:NO Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:HYDROCORTISONE ACETATE:MILD SKIN
IRRITATION. NEOMYCIN SULFATE:MILD SKIN IRRITATION. POSSIBLE
IRREVERSABLE DEAFNESS. POSSIBLE SENSITIZATION WTHEREPEUTIC USE. G/I
EFFECTS. COLISTIN SULFATE:BRONCHIAL IR RITATION. POSSIBLE
RESPIRATORY ARREST, REVERSABLE NEPHROTOXICITY, PARESTHESIA,
ITCHING, URTICARIA, DYSPNEA, CYANOSIS.
Explanation of Carcinogenicity:MANUFACTURER GAVE NO COMMENTS OTHER THAN
THE ABOVE REFERENCES TO THE THREE LISTINGS.
Effects of Overexposure:HYDROCORTISONE ACETATE:MILD SKIN IRRITATION.
NEOMYCIN SULFATE:MILD SKIN IRRITATION. POSSIBLE IRREVERSABLE
DEAFNESS. POSSIBLE SENSITIZATION WTHEREPEUTIC USE. G/I EFFECTS.
COLISTIN SULFATE:BRONCHIAL IR RITATION. POSSIBLE RESPIRATORY
ARREST, REVERSABLE NEPHROTOXICITY, PARESTHESIA, ITCHING, URTICARIA,
DYSPNEA, CYANOSIS.
Medical Cond Aggravated by Exposure:NO INFORMATION GIVEN ON MSDS BY
MFR.

First Aid:EYE:FLUSH WITH WATER FOR 15 MINUTES. IF IRRITATION PERSISTS,
GET MEDICAL ATTENTION. SKIN:WASH WITH SOAP & WATER UNTIL FREE OF
RESIDUE. INGESTION:GET IMMEDIATE MEDICAL ATTENTION.
INHALATION:REMOVE TO FRESH AIR. GET MEDICAL ATTENTION.

Flash Point:"NO DATA FOUND"
Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, FOAM, OR DRY CHEMICAL.
Fire Fighting Procedures:USE APPROVED SELF CONTAINED BREATHING
APPARATUS.
Unusual Fire/Explosion Hazard:"NO DATA FOUND"

Spill Release Procedures:PREVENT EXPOSURE. WIPE OR MOP UP SPILLED
MATERIAL. WASH ALL CONTAMINATED SURFACES WITH SOAP & WATER. PLACE
WASTE IN APPROPRIATELY LABELED, SEALED CONTAINER FOR FUTURE
DISPOSAL.
Neutralizing Agent:NO INFORMATION GIVEN ON MSDS BY MFR.

Handling and Storage Precautions:STORE AS STATED ON LABEL. HANDLE IN
SUCH A WAY AS TO AVOID SKIN AND EYE CONTACT. SHOULD CONTACT OCCUR,
WASH CONTAMINATED SKIN PROMPTLY.
Other Precautions:LAUNDER CONTAMINATED CLOTHING AND CONTAMINATED
EQUIPMENT BEFORE REUSE.

Respiratory Protection:NO INFORMATION GIVEN ON MSDS BY MFR.
Ventilation:NO INFORMATION GIVEN ON MSDS BY MFR.
Protective Gloves:NO INFORMATION GIVEN ON MSDS BY MFR.
Eye Protection:NO INFORMATION GIVEN ON MSDS BY MFR.
Other Protective Equipment:NO INFORMATION GIVEN ON MSDS BY MFR.
Work Hygienic Practices:MFR: ? HMIS:USE GOOD CHEMICAL HYGIENE
PRACTICE. AVOID UNNECESSARY CONTACT. WASH THOROUGHLY BEFORE EATING
OR DRINKING.
Supplemental Safety and Health
THIS MEDICINE IS USED AS ANTIBIOTIC. OCCURRANCE OF THE LISTED EFFECTS
IN THE OCCUPATIONAL SETTING IS CONSIDERED UNLIKELY. LD50 ORAL
MOUSE = 793 MG/KG FOR COLISTIN SULFATE. LD50 S.C. RAT = 200 MG/KG
FOR NEOMYCIN SULFATE. LD50 S.C. MOUSE= 45 MG/KG FOR HYDROCORTISONE
ACETATE.

HCC:N1
NRC/State Lic Num:NONE
Spec Gravity:1.016
pH:5.0

Stability Indicator/Materials to Avoid:YES
NO INFORMATION GIVEN ON MSDS BY MFR.
Stability Condition to Avoid:"UNDER LABELED STORAGE CONDITIONS SHIS
PRODUCT IS STABLE AND HAZARDOUS POLYMERIZATION WILL NOT OCCUR."
Hazardous Decomposition Products:NO INFORMATION GIVEN ON MSDS BY MFR.
Conditions to Avoid Polymerization:WILL NOT OCCUR

Waste Disposal Methods:DUE TO TRACE AMOUNT OF MERCURY FOUND IN THIS
PRODUCT, DISPOSE OF AS A HAZARDOUS WASTE I/A/W FEDERAL, STATE &
LOCAL REGULATIONS OR THE AUTHORITY HAVING JURISDICTION.
INCINERATION IN A PERMITTED INCINE RATOR IS PREFERRED, FOLLOWED BY
SOLIDIFICATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.