Product ID:FENTANYL CITRATE INJECTION USP, 9096
MSDS Date:06/03/1991
FSC:6505
NIIN:00N044278
MSDS Number: BTLTJ

ABBOTT LABORATORIES

HOSPITAL PRODUCTS DIVISION
ABBOTT PARK, IL 60064
US

Emergency Phone: 708-937-6100

Info Phone: 708-937-6100

Cage: 70048

ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV

NORTH CHICAGO, IL 60064-3500 US

Telephone: 847-935-7155

Cage: 70048

PROPIONANILIDE, N-(1-PHENETHYL-4-PIPERIDYL)-, CITRATE

CAS: 990-73-8

RTECS: UE5600000

OSHA PEL N/K

ACGIH TLV: N/K

OVERDOSE PRODUCES THE SAME EFFECTS WHICH IF NOT

RTECS: 9999999ZZ

LD50 LC50 Mixture:LD50 (ORAL/RAT): 18-136 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:FENTANYL CITRATE IS A POTENT NARCOTIC
ANALGESIC THAT IS 100 TIMES MORE POTENT THAN MORPHINE. IT IS USED
THERAPEUTICALLY TO PRODUCE ANALGESIA (PAIN RELIEF) & SEDATION.
FENTANYL CITRATE CAN CAUSE RESPIR ATORY DEPRESSION, REDUCED HEART
RATE & MUSCLE RIGIDITY. IN REPROD STUDIES IN RATS FENTANYL CITRATE
(EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT
Effects of Overexposure:HLTH HAZ: ADMIN RESULTED IN DECREASE IN
PREGNANCY RATE AT 12.5 TIMES THE HUMAN DOSE & AN EMBRYOCIDAL EFT AT
0.3 TIMES THE HUMAN DOSE. FENTANYL CITRATE CAN PRODUCE DRUG
DEPENDENCE OF THE MORPHINE TYPE AND HAS POTENTIAL FOR BEING
ABUSED. SIGNS & SYMPS: CLINICALLY, OVEREXP CAN PRODUCE RESP DEPRESS
(BRTHG (SUPP DATA)
Medical Cond Aggravated by Exposure:CNDTNS ASSOCIATED W/IMPAIRED RESP,
LIVER OR KIDNEY DYSFUNCTION, HEART DISEASE & CONCURRENT USE OF CNS
DEPRESSANT DRUGS.

First Aid:INHAL:REMOVE FROM SOURCE OF EXPOSURE. SKIN/ EYE: FLUSH
W/COPIOUS AMTS OF WATER FOR AT LST 15 MIN. IF IRRIT PERSISTS OR
SIGNS OF TOX OCCUR, SEEK MED ATTN. SPECIFIC NARCOTIC ANTAGONISTS,
E.G., NALORPHIN E HYDROBROMIDE OR NALOXONE HYDROCHLORIDE, &
ANTIDOTES FOR RESP DEPRESS PRODUCED BY FENTANYL CITRATE. PROVIDE
SYMPTOMATIC/SUPPORTIVE CARE AS NEC. INGEST: GET MD IMMED .

Flash Point:NON-FLAMMABLE
Extinguishing Media:EXTINGUISHING MEDIA SUITABLE FOR SURROUNDING FIRE .
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED SCBA AND FULL
PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:NONE SPECIFIED BY MANUFACTURER.

Spill Release Procedures:ABSORB WITH SUITABLE MATERIAL, FLUSH WITH
WATER AND METHANOL.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:NONE SPECIFIED BY MANUFACTURER.
Other Precautions:NONE SPECIFIED BY MANUFACTURER.

Respiratory Protection:NONE REQUIRED. NIOSH/MSHA APPROVED RESPIRATOR
APPROPRIATE FOR EXPOSURE OF CONCERN .
Ventilation:NO SPECIAL PROVISIONS REQUIRED.
Protective Gloves:RUBBER GLOVES.
Eye Protection:ANSI APPROVED CHEM SAFETY GOGGLES
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
EFTS OF OVEREXP: DIFFICULTIES), REDUCED HEART RATE AND MUSCLE RIGIDITY.
OTHER ADVERSE RXNS INCL CHANGES IN BLOOD PRESS, DIZZ, BLURRED
VISION, NAUSEA, EMESIS, LARYNGOSPASM & PERSPIRATION. OPIOID ANALGE
SICS PRODUCE EUPHORIA, MIOSIS (CONSTRICTION OF PUPILS), REDUCED
HEART RATE & BRONCHOCONSTRICTION. (ING 2)

HCC:T3
Boiling Pt:B.P. Text:WATER
Spec Gravity:WATER
pH:4-7.5
Solubility in Water:AQUEOUS SOLUTION
Appearance and Odor:CLEAR LIQUID.
Percent Volatiles by Volume:NEGLIG

Stability Indicator/Materials to Avoid:YES
NONE
Stability Condition to Avoid:NONE
Hazardous Decomposition Products:WHEN HEATED TO DECOMPOSITION, IT EMITS
TOXIC FUMES OF OXIDES OF NITROGEN.

Waste Disposal Methods:DISPOSE OF SOLUTION IN SEWER. BURY IN LANDFILL.
DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE AND FEDERAL REGULATIONS
.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.