Product ID:ZANTAC
MSDS Date:10/01/1988
FSC:6505
NIIN:01-275-6059
MSDS Number: BWMJN

Emergency Phone: 919-248-2100/2700

Info Phone: 919-248-2354

Cage: 34006

Telephone: 919-248-2100

Cage: 34006

RANITIDINE HYDROCHLORIDE

RTECS: KM6557000

Fraction By Weight: 100%

LD50 LC50 Mixture:LD50 ORAL, RAT= 4190MG/KG.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:CHRONIC OVEREXPO MAY CAUSE SKIN
RASH,NASAL SYMPTOMS,SHORTNESS OF BREATH
W/WHEEZING.SKIN:IRRIT,RASH.REPEATED CONTACT CAN LEAD TO
SENSITIZATION RESULTING IN ITCHY,RED ALLERGIC SKIN RASH.INHAL:IRRIT
MUC MEMB.EYE:IRRIT.INGEST:HEADACHE(SOMETIMES SEVERE),REVERSIBLE
INFLAMM OF LIVER ACCOMPANIED BY JAUNDICE.
Explanation of Carcinogenicity:PER MSDS:THERE'S NO PUBLISHED EVIDENCE
TO SHOW THAT COMPOUND IS CARCINOGENIC OR TERATOGENIC.
Effects of Overexposure:SKIN:IRRIT,RASH,SENSITIZATION,ITCHY RED ALLERGI
SKIN RASH. INHAL:IRRIT OF MUC MEMBRANES,NASAL CONGESTION/RUNNY
NOSE,SHORTNESS OF BREATH &
WHEEZING.EYE:IRRIT.INGEST:HEADACHE,REVERSIBLE INFLAMMATION OF
LIVER,JAUNDICE(YELLOWING OF SKIN & EYES).
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MFG.
NOTE:RANITIDINE HYDROCHLORIDE IS H2 RECEPTOR BLOCKER USED TO TREAT
PEPTIC ULCERS & TOHER GASTROINTESTINAL CONDITIONS. USUAL ADULT DOSE
IS 150MG TWICE DAILY.

First Aid:EYES:FLUSH W/LG AMTS OF WATER. SEEK MED ATTN. SKIN:REMOVE
CONTAMIN CLOTHING. WASH SKIN W/SOAP & WATER. INHAL:REMOVE TO FRESH
AIR. IF BREATH DIFFICULTY OR CEASES GIVE OXYGEN OR CARDIOPULMONARY
RESUSCIT ATION. SEEK MED ATTN FOR ANY RESP SYMPTOMS. INGEST:RINSE
MOUTH. GIVE LG QUANTITIES OF WATER & ENCOURAGE VOMITING. SEEK MED
ATTN.

Extinguishing Media:WATER SPRAY, FOAM, MULTI-PURPOSE DRY CHEMICAL.
Fire Fighting Procedures:WEAR FULL PROTECTIVE CLOTHING & USE
SELF-CONTAINED BREATHING APPARATUS (SCBA).
Unusual Fire/Explosion Hazard:AS W/ANY ORGANIC DUST THERE IS POTENTIAL
FOR EXPLOSION WHEN SUSPENDED IN AIR IN HIGH CONCENTRATIONS.

Spill Release Procedures:WEAR FULL PROT EQMPT WHEN POTENTIAL OF SKIN
EXPO/DUST INHAL.USE SCBA,SUPPLIED AIR RESP,AIR PURIFYING
RESP.UTILIZE GLOVES/EYE PROT/PROT CLOTH.COLLECT BY CAREFYLLY
SWEEP/VACUUM W/HEPA FILTER VACUUM.PLAC E IN CNTNR FOR
REUSE/DISPOSAL.WASH W/WATER AFT VAC

Handling and Storage Precautions:USE STORAGE PRACTICES THAT WILL
MINIMIZE GENERATION OF DUST.
Other Precautions:ALL SKIN CONTACT SHOULD BE AVOIDED. SPECIAL CARE
SHOULD BE TAKEN TO INSURE THAT CONTAMINATED CLOTHING & EQMPT ARE
PROPERLY CLEANED AFTER USE.

Respiratory Protection:RESP PROT EQMPT SHOULD BE WORN WHEN EXPO TO
AIRBONRE DUST LEVELS THAT EXCEED ESTIMATED SAFE WORKING
LEVEL.RECOMMENDATIONS FOR RESP SELECTION ISSUED BY NIOSH,ANSI
Z88.2,RESP EQPMT MFG SHOULD BE FOLLOWE D.
Ventilation:PROVIDE LOCAL EXHAUST VENTILATION SYSTEM @THE SOURCE OF
DUST GENERATION.
Protective Gloves:PROTECTIVE GLOVES
Eye Protection:FULL SKIN COVERINGS FOR EYE PROTECTION
Other Protective Equipment:PROT OUTER GARMENT MAY PROVIDE ADEQUATE
WORKER PROTECTION FOR LOW DUST EXPO.FULL BODY PROT FOR DUSTY AREAS.
Work Hygienic Practices:EMPOLOYEES EXPOSED TO DUST SHOULD CHANGE
CLOTHES & SHOWER AT END OF WORK ASSIGNMENT.
Supplemental Safety and Health

HCC:N1
Melt/Freeze Pt:M.P/F.P Text:272F,133C
Decomp Temp:Decomp Text:300F,149C
Solubility in Water:COMPLETE,VERY SOLUBL
Appearance and Odor:OFF-WHITE TO PALE YELLOW COLORED POWDER;
CHARACTERISTIC SULFUR-LIKE ODOR.

Stability Indicator/Materials to Avoid:YES
NO KNOWN INCOMPATIBILITIES.
Stability Condition to Avoid:EXTREME HEAT:MATERIAL DECOMPOSES @300F.
Hazardous Decomposition Products:THERMAL DECOMPOSITION PRODUCTS INCLUDE
TOXIC &/OR CORROSIVE VAPORS CONSISTING OF CHLORIDES & OXIDES OF
NITROGEN & SULFUR

Waste Disposal Methods:INCINERATE AT APPROVED FACILITY IN ACCORDANCE
WITH LOCAL, STATE AND FEDERAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.