Product ID:BUPRENEX
MSDS Date:07/14/1992
FSC:6505
NIIN:01-224-0160
MSDS Number: BXPBT

Emergency Phone: 804-379-1090

Info Phone: 804-379-1090

Cage: RECKI

Telephone: 201-633-6700

Cage: 0TTK4

BUPRENORPHINE HYDROCHLORIDE *95-1*

CAS: 53152-21-9

RTECS: KM7758000

Fraction By Weight: 0.3%

LD50 LC50 Mixture:ORAL LD50(MUS): 800 MG/KG (SEE SUPP)
Routes of Entry: Inhalation:NO Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:UPON INJECTION, SEDATION,
NAUSEA/DIZZINESS, UNKNOWN EFFECTS FROM INHALATION, INGESTION/SKIN
CONTACT.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:UPON INJECTION, SEDATION, NAUSEA/DIZZINESS,
UNKNOWN EFFECTS FROM INHALATION, INGESTION/SKIN CONTACT.
Medical Cond Aggravated by Exposure:HEPATIC, PULMONARY/RENAL FUNCTION
IMPAIRMENT: MYXEDEMA, HYPOTHYROIDISM: ADDISON'S DISEASE.

First Aid:OBTAIN MEDICAL ATTENTION IN ALL CASES.

Extinguishing Media:WATER, CO2, DRY POWDER

Spill Release Procedures:VACUUM/SWEEP, PLACE IN CONTAINERS. IF AMPULES
ARE BROKEN, USE DUST MASK & GLOVES FOR DISPOSAL PROCEDURES.

Handling and Storage Precautions:IF AMPULES ARE BROKEN, USE DUST MASK &
GLOVES. FOLLOW SANITARY DISPOSAL FOR SYRINGES.

Protective Gloves:RECOMMENDED IF AMPULES ARE BROKEN
Work Hygienic Practices:WASH AFTER CONTACT W/POWDER.
Supplemental Safety and Health
ORAL LD50 INFORMAITON IS FOR: BUPRENORPHINE HYDROCHLORIDE.

Decomp Temp:Decomp Text:>140F
pH:<7
Solubility in Water:SLIGHT
Appearance and Odor:WHITE POWDER/CLEAR LIQUID FOR INJECTION

Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:HIGH HEAT, LIGHT

Waste Disposal Methods:INCINERATE, LANDFILL/SECONDARY TREATMENT IN
ACCORDANCE W/LOCAL, STATE & FEDERAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.