Product ID:CYTOVENE
MSDS Date:10/09/1992
FSC:6505
NIIN:01-307-8496
MSDS Number: BYPDT

SYNTEX INC

3401 HILLVIEW AVE
PALO ALTO, CA 94304-5000
US

Emergency Phone: 415-796-5050

Info Phone: 415-796-5050

Cage: 0Y3S3

SYNTEX INC

PALO ALTO, CA 94304-5000 US

Telephone: 415-855-5050

Cage: 0Y3S3

GANCICLOVIR SODIUM

CAS: 84245-13-6

Fraction By Weight: 500% MG

WATER

CAS: 7732-18-5

RTECS: ZC0110000

Fraction By Weight: 10% ML

Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:SKIN/EYES: IRRITATION. INHALATION:
POWDER MAY CAUSE MUCOUS MEMBRANE & RESPIRATORY IRRITATION. REPEATED
OVEREXPOSURE MAY CAUSE BLOOD DISORDERS, BIRTH DEFECTS & CANCER.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION.

First Aid:EYES: IMMEDIATELY FLUSH THOROUGHLY W/WATER FOR 15 MINS. SKIN:
IMMEDIATELY WASH THOROUGHLY W/SOAP & WATER FOR 15 MINS. INHALATION:
IMMMEDIATELY REMOVE TO FRESH AIR. INGESTION: DRINK A MODERATE
AMOUNT ( 8-12 OZ/250 ML) OF WATER. OBTAIN MEDICAL ATTENTION IN ALL
CASES.

Extinguishing Media:WATER, MULTIPURPOSE DRY CHEMICAL/HALON FIRE
EXTINGUISHER.
Fire Fighting Procedures:WEAR FULL PROTECTIVE CLOTHING & NIOSH/MSHA
APPROVED, POSITIVE PRESSURE, SCBA. WASH ALL EQUIPMENT THOROUGHLY
AFTER USE.

Spill Release Procedures:USE APPROPRIATE PERSONAL PROTECTIVE EQUIPMENT.
CONTAIN & MINIMIZE THE SPREADING OF MATERIAL. FOR POWDER: DON'T
ATTEMPT TO SWEEP UP MATERIAL, USE WATER/AN APPROPRIATE LIQUID TO
WET DOWN POWDER. SOAK UP MATERIAL W/ABSORBENT. (SEE SUPP)

Handling and Storage Precautions:STORE IN A COOL, WELL-VENTILATED AREA.
USE ADEQUATE VENTILATION TO MINIMIZE EXPOSURE.
Other Precautions:AVOID CONTACT W/SKIN, EYES/CLOTHING. MATERIAL IS
INTENDED FOR HUMAN PHARMACUTICAL USE BY INTRAVENOUS INFUSION AS
PRESCRIBED BY PHYSICIAN. AS CONTAINED IN BOTTLES & CARTONS,
SHOULDN'T RESULT IN EXPOSUR E/PRESENT A HAZARD.

Respiratory Protection:IF RECONSITUTION OF GANCICLOVIR SODIUM W/IN AN
APPROVED BIOLIGICAL SAFETY CABINET ISN'T POSSIBLE, A PROPERLY
FITTED NIOSH/MSHA APPROVED DISPOSABLE DUST/MIST MASK SHOULD BE
CONSIDERED.
Protective Gloves:LATEX
Eye Protection:SAFETY GLASSES W/SIDE SHIELDS
Other Protective Equipment:LAB COAT, PROTECTIVE OVER GARMENT.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
PH: ADJUSTED TO 10.8-11.4 W/SODIUM HYDROXIDE FOR RECONSTITUTION. WASTE
DISPOSAL CONT'D: ALL WASTE MATERIAL SHOULD BE LABELED & STORED
SEPARATELY.

Melt/Freeze Pt:M.P/F.P Text:467.6-491F
Decomp Temp:Decomp Text:467.6-491F
Vapor Pres:(SUPP)
Vapor Density:0
pH:(SUPP)
Evaporation Rate & Reference:0
Solubility in Water:COMPLETE (HOT WATER)
Appearance and Odor:WHITE, ODORLESS W/LYOPHILIZED POWDER
Percent Volatiles by Volume:0

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS
Stability Condition to Avoid:PHARMACOLOGIC STABILITY NOT GUARANTEED
BEYOND EXPIRATION DATE.
Hazardous Decomposition Products:CO, CO2, NITROGEN OXIDES

Waste Disposal Methods:DISPOSE OF WASTE MATERIAL IN A PERMITTED
CHEMICAL WASTE INCINERATOR IAW/FEDERAL, STATE & LOCAL REGULATIONS.
RINSEWATER FROM SPILL CLEANUPS SHOULD BE DISCHARGED IN AN
ENVIRONMENTALLY SAFE MANNER TO A P ERMITTED WASTEWATER TREATMENT
FACILITY.(SEE SUPP)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.