Product ID:WALPB003 ATIVAN INJECTION
MSDS Date:08/05/1995
FSC:6505
NIIN:01-372-8440
MSDS Number: CCVVF

WYETH-AYERST LABORATORIES

PHILADELPHIA, PA 19101
US

Emergency Phone: 610-688-4400(CHEMTREC 800-424-9300)

Info Phone: 610-688-4400

Cage: 0HMG4

WYETH-AYERST LABORATORIES

PHILADELPHIA, PA 19101-5000 US

Telephone: 610-902-5171

Cage: 0HMG4

LORAZEPAM OR ATIVAN OR LORAX

CAS: 846-49-1

RTECS: DF0350000

Fraction By Weight: 0.2-0.4%

BENZYL ALCOHOL

CAS: 100-51-6

RTECS: DN3150000

Fraction By Weight: >1%

POLYETHYLENE GLYCOL (MFR SAYS POLYETHYLENE GLYCOL 400)

CAS: 25322-68-3

RTECS: TQ3500000

Fraction By Weight: >1%

PROPYLENE GLYCOL

CAS: 57-55-6

RTECS: TY2000000

Fraction By Weight: >1%

Routes of Entry: Inhalation:NO Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MODERATELY TOXIC BY INGESTION;
CENTRAL NERVOUS SYSTEM DEPRESSANT. USE OF ALCOHOL MAY ENHANCE TOXIC
EFFECTS. INTERACTIONS WITH MEDICATIONS HAS BEEN REPORTED. POISONING
MAY IMPAIR TASKS REQUIRING ALERTNESS. MAY CROSS THE PLACENTA & MAY
BE EXCRETED IN HUMAN BREAST MILK. CHRONIC: NONE SPECIFIED BY
MANUFACTURER.
Explanation of Carcinogenicity:NO INGREDIENT OF A CONCENTRATION OF 0.1%
OR GREATER IS LISTED AS A CARCINOGEN OR SUSPECTED CARCINOGEN.
Effects of Overexposure:HEADACHE, NAUSEA, VOMITING, EPIGASTRIC
DISTRESS, DIARRHEA, INCONTINENCE, DROWSINESS, FATIGUE, DIZZINESS,
WEAKNESS, MUSCLE RELAXATION, ARAXIA, DYSARTHRIA, CHANGE IN
SALAVATION, SLURRED SPEECH, BITTER T ASTE, DILATED PUPILS,
DIPLOPIA, NYSTAGUS, BLURRED VISION, IRRITABILITY, IMPAIRED MENTAL &
PSYCOMOTOR FUNCTION...........
Medical Cond Aggravated by Exposure:PRESONS WITH LIVER OR RENAL
IMPAIRMENT, ACUTE NARROW-ANGLE GLAUCOMA, HYPERSENSITIVITY TO
BENZODIAZEPINES, PERSONALITY DISORDERS OR HISTORY OF DRUG ABUSE.

First Aid:IN ALL CASES GET IMMEDIATE MEDICAL ATTENTION. EYES-FLUSH WITH
WATER FOR 15 MINUTES. SKIN-REMOVE CONTAMINATED CLOTHES. WASH WITH
MILD SOAP & WATER. INHALED-REMOVE TO FRESH AIR. GIVE OXYGEN OR
ARTIFICIA L RESPIRATION AS NEEDED. INGESTED-IF VOMITING OCCURS,
KEEP HEAD BELOW HIPS. TREAT SYMPTOMATICALLY & SUPPORTIVELY.

Flash Point:>213F,>101C
Extinguishing Media:USE MEDIA APPROPRIATE FOR SURROUNDING FIRE-WATER
FOG, CARBON DIOXIDE, DRY CHEMICAL, REGULAR FOAM.
Fire Fighting Procedures:MOVE CONTAINER FORM FIRE AREA IF CAN BE DONE
W/O RISK. DO NOT SCATTER SPILLED MATERIAL WITH HIGH PRESSURE
STREAMS. DIKE FIRE CONTROL WATER FOR LATER DISPOSAL.
Unusual Fire/Explosion Hazard:SLIGHT FIRE HAZARD WHEN EXPSOED TO HEAT
OR FLAME.

Spill Release Procedures:ELIMINATE ALL SOURCES OF IGNITION.STOP LEAK IF
NO RISK.USE WATER SPRAY TO REDUCE VAPOR.TAKE UP WITH ABSORBENT
MATERIAL & PLACE INTO CONTAINER FOR LATER DISPOSAL.LARGER
SPILLS:DIKE TO CONTAIN.ISOLATE & DENY ENTRY.STAY UPWIND,KEEP OUT
OF LOWARES.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE IN A COOL, DRY PLACE AWAY FROM
INCOMPATIBLE MATERIALS. STORAGE OF CONTROLLED SUBSTANCES MUST
COMPLY WITH APPLICABLE SECURITY REQUIREMENTS.
Other Precautions:SECURITY REQUIREMENTS: 21 CFR 1301.71-1301.76.

Respiratory Protection:IF ENGINEERING CONTROLS FAIL OR NON-ROUTINE USE
OR AN EMERGENCY OCCURS; WEAR AN MSHA/NIOSH APPROVED RESPIRATOR WITH
ORGANIC VAPOR CARTRIDGE OR AN AIR-SUPPLIED RESPIRATOR OR SCBA, AS
REQUIRED. USE IAW 29 CFR 1910.134.
Ventilation:USE ADEQUATE MECHANICAL VENTILATION OR LOCAL EXHAUST TO
MAINTAIN EXPOSURE BELOW TLV(S).
Protective Gloves:NONE NORMALLY REQUIRED-ARE RECOMMENDED.
Eye Protection:SPLASH-RESISTANT SAFETY GLASSES.
Other Protective Equipment:NONE NORMALLY REQUIRED. DLA-HMIS: EYE WASH
STATION, WASHING FACILITIES AVAILABLE.
Work Hygienic Practices:WASH HANDS AFTER HANDLING AND BEFORE EATING,
DRINKING, OR SMOKING. LAUNDER CONTAMINATED CLOTHES BEFORE REUSE.
Supplemental Safety and Health
NONE.

HCC:T4
Appearance and Odor:CLEAR, AQUEOUS SOLUTION.

Stability Indicator/Materials to Avoid:YES
ACIDS, BASES, & OXIDIZERS.
Stability Condition to Avoid:MAY BURN BUT DOES NOT READILY IGNITE.
AVOID CONTACT WITH STRONG OXIDIZERS, EXCESSIVE HEAT, SPARKS, OR
OPEN FLAMES.
Hazardous Decomposition Products:THERMAL DECOMPOSITION MAY RELEASE
TOXIC AND/OR HAZARDOUS GASES.
Conditions to Avoid Polymerization:HAZARDOUS POLYMERIZATION HAS NOT
BEEN REPORTED TO OCCUR UNDER NORMAL TEMPERATURES AND PRESSURES.

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE AND
FEDERAL ENVIRONMENTAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.