Product ID:IMX HOMOCYSTEINE ENZYME (HYDROLASE) REAGENT BOTTTLE(SUPDAT)
MSDS Date:09/23/1998
FSC:6550
NIIN:00N091340
Status Code:A
MSDS Number: CJJKR

ABBOTT LABORATORIES

100 ABBOTT PARK RD
ABBOTT PARK, IL 60064-3500
US

Emergency Phone: 847-937-7970

Info Phone: 847-937-3386

Cage: 33110

ABBOTT LABORATORIES INC DIAGNOSTICS DIV

NORTH CHICAGO, IL 60064 US

Telephone: 847-935-7177

Cage: 33110

GLYCEROL

CAS: 56-81-5

RTECS: MA8050000

OSHA PEL 15 MG/M3

ACGIH TLV: 10 MG/M3

SODIUM AZIDE

CAS: 26628-22-8

RTECS: VY8050000

EPA Report Quantity: 1000 LBS

DOT Report Quantity: 1000 LBS

WATER

CAS: 7732-18-5

RTECS: ZC0110000

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION.
Routes of Entry: Inhalation:YES Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:PRIMARY IRRITANT EFFECT: ON THE SKIN:
NO IRRITANT EFFECT. ON THE EYE: NO IRRITANT EFFECT. SENSITIZATION:
NO SENSITIZING EFFECTS KNOWN. TARGET ORGANS/SYSTEMS: KIDNEYS.
Explanation of Carcinogenicity:THIS PRODUCT DOES NOT CONTAIN
CARCINOGENS LISTED BY IARC, NTP, OSHA OR ACGIH.
Effects of Overexposure:SEE HEALTH HAZARDS.
Medical Cond Aggravated by Exposure:PRE-EXISTING RENAL AILMENTS.

First Aid:INHAL:REMOVE FROM SOURCE OF EXPOS. IF SIGNS OF TOX OCCUR,
SEEK MED ATTN. PROVIDE SYMPTOMATIC/SUPPORTIVE CARE AS NEEDED.
SKIN:REMOVE FROM SOURCE OF EXPOS. FLUSH W/COPIOUS AMTS OF WATER. IF
IRRIT PERSIS TS/SIGNS OF TOX OCCUR, SEEK MED ATTN. PROVIDE
SYMPTOMATIC/SUPPORTIVE CARE AS NEC. EYES:REMOVE FROM SOURCE OF
EXPOS. FLUSH W/COPIOUS AMTS OF WATER FOR AT LST 15 MINS. IF IRRIT
PERSISTS/SIGNS OF TOX OCC UR, SEEK MED ATTN. PROVIDE
SYMPTOMATIC/SUPPORTIVE CARE AS NEC. INGEST:REMOVE FROM SOURCE OF
EXPOS. IF SIGNS OF TOX OCCUR, SEEK MED ATTN. PROVIDE
SYMPTOMATIC/SUPPORTIVE CARE AS NEC.

Autoignition Temp:=400.C, 752.F
Autoignition Temp Text:SUPDAT
Lower Limits:0.9%
Extinguishing Media:CO*2, EXTINGUISHING POWDER OR WATER SPRAY. FIGHT
LARGER FIRES WITH WATER SPRAY OR ALCOHOL RESISTANT FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:PRODUCT DOES NOT PRESENT AN EXPLOSION
HAZARD. NFPA RATINGS: HEALTH - 0; FIRE - 0; REACTIVITY - 0.
INTERNAL ABBOTT (CHAP) & OSHA HAZARD RATINGS: CHAP: HEALTH - 0
(MINIMAL RISK); FIRE - 0; REACTIVITY - 0; SPECIAL HAZARDS: NONE.
OSHA: NON-HAZARDOUS; NONCOMBUSTIBLE.

Spill Release Procedures:NO SPECIAL WORK PRACTICES REQUIRED. CONTAIN
SPILL WITH APPROPRIATE ABSORBANT MATERIAL. ABSORB WITH
LIQUID-BINDING MATERIAL (SAND, DIATOMITE, ACID BINDERS, UNIVERSAL
BINDERS, SAWDUST). NO DANGEROUS SUB STANCES ARE RELEASED.

Handling and Storage Precautions:NO SPECIAL HNDLG PRECS ARE NECESSARY
IF USED CORRECTLY. NO SPECIAL STORAGE REQUIREMENTS TO BE MET BY
STOREROOMS & RECEPTACLES. INFO ABOUT STORAGE IN ONE COMMON STORAGE
FACILITY: NOT REQUIRED. FURTHER INFO ABOUT STORAGE CNDTNS: PROTECT
FROM HEAT & DIRECT SUNLIGHT. STORAGE CLASS: N/A.
Other Precautions:NO SPECIAL MEASURES REQUIRED FOR PROTECTION AGAINST
EXPLOSIONS & FIRES. CLASS ACCORDING TO REGULATION ON FLAMMABLE
LIQUIDS: NOT APPLICABLE.

Respiratory Protection:THE APPROPRIATE NIOSH APPROVED RESPIRATORY
PROTECTION SHOULD BE USED IF AIRBORNE CHEMICAL CONCENTRATION
EXCEEDS THE EXPOSURE LIMITS.
Ventilation:NOT NECESSARY IF ROOM IS WELL-VENTILATED.
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH & DELUGE SHOWER MTG ANSI DESIGN
CRIT . BODY PROTECTION NOT NEEDED FOR SMALL QTY USAGE. THE NEED FOR
APPROPRIATE BODY PROTECTION SHOULD BE DETERMINED ON A CASE BY CASE
BASIS.
Work Hygienic Practices:THE USUAL PRECAUTIONARY MEASURES FOR HANDLING
CHEMICALS SHOULD BE FOLLOWED.
Supplemental Safety and Health
PRODUCT IDENTITY: 2, 2600141. FIRE AND EXPLOSION HAZARD: AUTO
IGNITION:PRODUCT IS NOT SELF-IGNITING.

Boiling Pt:B.P. Text:NOT DETERMINED
Melt/Freeze Pt:M.P/F.P Text:NOT DETERMINED
Vapor Pres:23.0 HPA @ 20C
Spec Gravity:1.090 G/CM3 @ 20C
pH:67.5 @ 20C
Solubility in Water:FULLY MISCIBLE
Appearance and Odor:COLORLESS LIQUID; ODORLESS.

Stability Indicator/Materials to Avoid:YES
NO DANGEROUS REACTIONS KNOWN.
Hazardous Decomposition Products:NO DECOMPOSITION IF USED ACCORDING TO
SPECIFICATIONS. NO DANGEROUS DECOMPOSITION PRODUCTS KNOWN.

Waste Disposal Methods:DISPOSE I/A/W FEDERAL, STATE AND LOCAL
REGULATIONS. RECOMMENDED CLEANSING AGENT FOR UNCLEANED PACKAGINGS:
WATER, IF NECESSARY WITH CLEANSING AGENTS.

Toxicological Information:ACUTE TOXICITY: LD/LC50 VALUES FOR HAZARDOUS
INGREDIENTS PER OSHA CRITERIA: CAS #56-86-5 - GLYCEROL:
LD50:(ORAL,MAMMAL) 4090 MG/KG. TDLO:(ORAL,HUMAN) 1428 MG/KG
W/HEADACHES, NAUSEA & VOMITING REPORTED . TDLO:(ORAL,HUMAN) 1428
MG/KG MG/KG/DA (CARCINOGEN). LD50: (DERMAL,RABBIT) >10,000 MG/KG.
LC50:(INHAL,RAT) 0.57 MG/L/1 HR. MUTAGENICITY: NEGATIVE (AMES
ASSAY). GENERALLY NEGATIVE IN AMES TEST. WHEN U SED & HANDLED
ACCORDING TO SPECIFICATIONS, PRODUCT DOES NOT HAVE ANY HARMFUL
EFFECTS ACCORDING TO OUR EXPERIENCE & INFORMATION PROVIDED TO US.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:NOT KOWN TO BE A WATER POLLUTANT.

Transport Information:DOT REGULATIONS: HAZARD CLASS: NOT REGULATED FOR
TRANSPORTATION. LAND TRANSPORT ADR/RID (CROSS-BORDER): ADR/RID
CLASS: NOT REGULATED FOR TRANSPORTATION. IMDG CLASS: MARINE
POLLUTANT: NO - NOT REGULATE D FOR TRANSPORTATION. AIR TRANSPORT
ICAO-TI AND IATA-DGR: ICAO/IATA CLASS: NOT REGULATED FOR
TRANSPORTATION.

SARA Title III Information:SARA: SECTION 302/302 (40 CFR 355.30/40 CFR
355.40): CAS #26628-22-8 - SODIUM AZIDE. SECTION 313 (40 CFR
372.65): CAS #26628-22-8 - SODIUM AZIDE.
Federal Regulatory Information:CLASSIFICATION WAS MADE ACCORDING TO
OSHA 29 CFR 1910.1200 & 1910.1030, & IS EXPANDED UPON FROM COMPANY
&/OR LITERATURE DATA. MARKINGS ACCORDING TO EUROPEAN GUIDELINES:
OBSERVE THE GENERAL SAFETY REGU LATIONS WHEN HANDLING CHEMICALS.
THE PRODUCT DOES NOT REQUIRE ANY HAZARD WARNINGS ACCORDING TO
RESPECTIVE EUROPEAN COMMUNITY (EC) DIRECTIVES.
State Regulatory Information:CALIFORNIA PROPOSITION 65 (U.S.A.):
CHEMICALS KNOWN TO CAUSE CANCER: THE PRODUCT DOES NOT CONTAIN
LISTED SUBSTANCES. CHEMICALS KNOWN TO CAUSE REPRODUCTIVE TOXICITY:
THE PRODUCT DOES NOT CONTAIN LISTED SUBSTANCES.