Product ID:DEOXYCHOLIC ACID, SODIUM SALT, 264101
MSDS Date:02/24/1999
FSC:6505
NIIN:00N092484
Status Code:A
MSDS Number: CJTCQ

Emergency Phone: (800)424-9300

Info Phone: 800-854-3417; 619-450-5558

Cage: 29089

Telephone: 619-450-5558; 800-854-3417

Cage: 29089

(ORAL, RAT) 1370 MG/KG

CAS: 302-95-4

RTECS: FZ2250000

LD50 LC50 Mixture:SEE INGRED & TOXICOLOGICAL INFO
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:MAY BE HARMFUL BY INGESTION,
INHALATION OR ABSORPTION THROUGH SKIN. MATERIAL MAY CAUSE
IRRITATION TO THE EYES, SKIN, MUCOUS MEMBRANES AND THE UPPER
RESPIRATORY TRACT.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:SKIN: IN CASES OF SKIN CONTACT, WASH IMMED W/COPIOUS AMOUNTS
OF WATER FOR AT LEAST 15 MINUTES. REMOVE CONTAMINATED CLOTHING AND
SHOES AND WASH BEFORE WEARING. CONSULT A MD. EYES: IN CASES OF EYE
CONTA CT, FLUSH IMMED W/COPIOUS AMOUNTS OF WATER FOR AT LEAST 15
MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING EYELIDS W/FINGERS.
CONSULT A MD. INHAL: IN CASES OF INHALATION, REMOVE TO FRESH AIR
AND MONIT OR BREATHING. IF BREATHING BECOMES DIFFICULT, GIVE OXYGEN
AND CONSULT A MD. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION
AND CONSULT A MD. INGEST: IN CASES OF INGESTION, WASH MOUTH OUT
W/WATER AND CONSULT LOCAL POISON CENTER AND A MD.

Extinguishing Media:DRY CHEMICAL POWDER, CARBON DIOXIDE, WATER SPRAY,
ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:UPON THERMAL DECOMPOSITION, IT MAY EMIT
TOXIC GASES.

Spill Release Procedures:EVACUATE AREA. WEAR A NIOSH APPROVED
RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. SWEEP UP AND PLACE IN A SUITABLE CONTAINER. AVOID RAISING
DUST. HOLD FOR APPROPRIATE DIS POSAL. WASH SPILL SITE AND VENTILATE
AREA AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:STORE IN A TIGHTLY CLOSED CONTAINER IN
A COOL, DRY PLACE (+20C). PROTECT FROM MOISTURE. MATERIAL IS
HARMFUL AND AN IRRITANT. AVOID CONTACT W/MATERIAL. AVOID PROLONGED
OR REPEATED EXPOSURE. LAB SHOULD BE EQUIPPED WITH A SAFETY SHOWER
AND AN EYE WASH STATION. WASH THOROUGHLY AFTER HANDLING MATERIAL.

Respiratory Protection:USE A NIOSH APPROVED RESPIRATOR.
Ventilation:HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves:CHEMICAL RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH AND DELUGE SHOWER .
WEAR SUITABLE PROTECTIVE CLOTHING.
Supplemental Safety and Health
DEOXYCHOLIC ACID, SODIUM SALT - MOLECULAR WEIGHT: 414.6; MOLECULAR
FORMULA: C*24H*39O*4-NA.

Solubility in Water:SOLUBLE
Appearance and Odor:OFF-WHITE SOLID.

Stability Indicator/Materials to Avoid:YES
N/A.
Stability Condition to Avoid:N/A. STABLE UNDER NORMAL HANDLING
PROCEDURES.
Hazardous Decomposition Products:UPON THERMAL DECOMPOSITION, MAY EMIT
TOXIC GASES INCLUDING CARBON MONOXIDE AND CARBON DIOXIDE.

Waste Disposal Methods:COUNTY, FEDERAL, STATE AND LOCAL REGULATIONS ARE
VARIED AND CHANGE FREQUENTLY. FOR THIS REASON, WE RECOMMEND THAT
YOU CONTACT YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR
INFORMATION ON DISPOSAL OF TH IS PRODUCT OR ARRANGE FOR DISPOSAL BY
A LICENSED DISPOSAL COMPANY.

Toxicological Information:RTECS NUMBER: FZ2250000. TOXICITY DATA &
REFERENCES: ORAL; RAT LD50: 1370 MG/KG ALTERED SLEEP; ATAXIA 1969.
OYO YAKURI. PHARMACOMETRICS. 3, 45. ORAL; MUS; LD50: 1050 MG/KG
SOMNOLENCE; ULCERATION/BLEED ING FROM STOMACH & SMALL INTESTINE
1985. EISEI SHIKENJO HOKOKU. BULLETIN OF THE INSTITUTE OF HYGIENIC
SCIENCES. (103), 29. IPR; RAT; LD50: 123 MG/KG ALTERED SLEEP;
ATAXIA 1969. OYO YAKURI. PHARMACOMET RICS. 3, 45. IPR; MUS; LD50:
36 MG/KG EXCITATION; HYPERMOTILITY; DIARRHEA 1985. EISEI SHIKENJO
HOKOKU. BULLETIN OF THE INSTITUE OF HYGIENIC SCIENCES. (103), 29.
IVN; RAT; LD50: 150 MG/KG 1970. (ECOLOG ICAL INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:NO INFORMATION AVAILABLE. --TOXICOLOGICAL INFO:
ARZNEIMITTEL-FORSCHUNG. DRUG RESEARCH. 20, 323. IVN; MUS; LD50: 107
MG/KG 1952. ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE
THERAPIE. 90, 18. SCU; MUS; LD50: 815 MG/KG ALTER SLEEP; ATAXIA
1969. OYO YAKURI. PHARMACOMETRICS. 3, 45. REPRODUCTIVE EFFECTS AND
REFERENCES: IPR; RAT; DOSE: 1400 MG/KG TOXIC PATERNAL EFFECTS 1969.
OYO YAKURI. PHARMACOMET RICS. 3, 45. GENETIC DATA & REFERENCES:
FBR; HMN; DOSE: 25 MG/L UNSCHEDULED DNA SYNTHESIS 1991. NUTRITION
AND CANCER. 16, 227. LYM; HMN; DOSE: 100 MG/L DNA INHIBITION 1982.
BULLETIN OF (TRANSPORT INFO )

Transport Information:UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA
CLASS: N/A. IATA PACKING GROUP: N/A. --ECOLOGICAL INFO:
ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY. 28, 504. REFER TO THE
REGISTRY OF TOXIC EFFECTS OF C HEMICAL SUBSTANCES (RTECS) FOR A
DEFINITION OF ABBREVIATIONS USED IN THE ABOVE TEXT AND FOR
ADDITIONAL INFORMATION. THIS REPORT CONTAINS ONLY SELECTED
INFORMATION FROM THE RTECS.

Federal Regulatory Information:RISK PHRASES: R20/21/22: HARMFUL BY
INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED. R36/37/38;
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. SAFETY PHRASES:
S22: DO NOT BREATHE DUST. S24/25: AVO ID CONTACT WITH SKIN AND
EYES. S26: IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH
PLENTY OF WATER AND SEEK MEDICAL ADVICE. S36/37/39: WEAR SUITABLE
PROTECTIVE CLOTHING, GLOVES AND EYE/FACE PROT ECTION. S45: IN CASE
OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY.
State Regulatory Information: