Product ID:ETHYL ACETATE PROTEIN SEQUENCING GRADE, E4893
MSDS Date:07/01/1999
FSC:6550
NIIN:00N092547
Status Code:A
MSDS Number: CJTDR

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

ACETIC ETHER

CAS: 141-78-6

RTECS: AH5425000

OSHA PEL 1400 MG/M3;400 PPM

ACGIH TLV: 1440 MG/M3;400 PPM

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

LD50 LC50 Mixture:LD50: (ORAL,RAT) 5620 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE HARMFUL BY INHALATION,
INGESTION, OR SKIN ABSORPTION. CAUSES SKIN IRRITATION. VAPOR OR
MIST IS IRRITATING TO EYES, MUCOUS MEMBRANES AND UPPER RESPIRATORY
TRACT. CAN CAUSE CNS DEPRESSION. PROLONGED EXPOSURE CAN CAUSE:
NAUSEA, HEADACHE AND VOMITING. NARCOTIC EFFECT. ANEMIA. TARGET
ORGAN(S): LIVER, KIDNEYS, CENTRAL NERVOUS SYSTEM, BLOOD.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:EYES: IMMEDIATELY FLUSH W/COPIOUS AMOUNTS OF WATER FOR AT
LEAST 15 MINUTES. SKIN: IMMEDIATELY WASH WITH SOAP & COPIOUS
AMOUNTS OF WATER. INHALED: REMOVE TO FRESH AIR. IF NOT BREATHNG
GIVE ARTIFICIAL R ESPIRATION. IF BREATHNG IS DIFFICULT, GIVE
OXYGEN. INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS
CONSCIOUS. CALL PHYSICIAN. WASH CONTAMINATED CLOTHNG BEFORE REUSE.

Flash Point Method:CC
Flash Point:=-4.4C, 24.F
Autoignition Temp:=426.C, 798.8F
Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE
FOAM. WATER MAY BE EFTIVE FOR COOLING, BUT MAY NOT EFFECT
EXTINGUISHMENT.
Fire Fighting Procedures:FLAMMABLE LIQUID. WEAR NIOSH APPROVED
SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHNG TO
PREVENT CONTACT WITH SKIN AND EYES. USE WATER SPRAY TO COOL
FIRE-EXPOSED CONTAINERS.
Unusual Fire/Explosion Hazard:VAPOR MAY TRAVEL CONSIDERABLE DISTANCE TO
SOURCE OF IGNITION AND FLASH BACK. CONTAINER EXPLOSION MAY OCCUR
UNDER FIRE CONDITIONS. FORMS EXPLOSIVE MIXTURES IN AIR.

Spill Release Procedures:EVACUATE AREA. SHUT OFF ALL SOURCES OF
IGNITION. WEAR NIOSH APPRVD SCBA, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. COVER WITH AN ACTIVATED CARBON ABSORBENT, TAKE UP AND PLACE
IN CLOSED CONTAINERS. TRASPOR T OUTDOORS. VENTILATE AREA AND WASH
SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:FLAMMABLE. IRRITANT. KEEP AWAY FROM
SOURCES OF IGNIT - NO SMOKING. WEAR SUITABLE PROT CLTHG. DO NOT
BREATHE VAPOR. DO NOT GET IN EYES, ON SKIN, ON CLOTHING. AVOID
PROLONGED OR REPEATED EXPOSURE.
Other Precautions:WASH THOROUGHLY AFTER HANDLING. KEEP TIGHTLY CLOSED.
KEEP AWAY FROM HEAT, SPARKS, AND OPEN FLAME. STORE IN A COOL DRY
PLACE.

Respiratory Protection:NIOSH APPROVED RESPIRATOR IN NONVENTILATED AREAS
AND/OR FOR EXPOSURE ABOVE THE ACGIH TLV.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:RUBBER GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER .
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
TOX INFO: SENSE ORGANS & SPEC SENSES (CONJUNCTIVA IRRIT). LUNGS,
THORAX/RESP (OTHER CHANGES). ONLY SELECTED REGISTRY OF TOXIC EFTS
OF CHEM SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY
I N RTECS FOR COMPLETE INFO.

Boiling Pt:=77.C, 170.6F
Melt/Freeze Pt:=-83.C, -117.4F
Vapor Pres:76 @ 20C
Vapor Density:3.04
Spec Gravity:0.89
Evaporation Rate & Reference:6 (BUAC =1)
Solubility in Water:SOLUBLE
Appearance and Odor:LIQUID.
Percent Volatiles by Volume:100

Stability Indicator/Materials to Avoid:YES
OXIDIZING AGENTS, BASES, ACIDS, MOISTURE, HEAT, SENSITIVE TO MOISTURE.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE.

Waste Disposal Methods:BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER BUT EXERT EXTRA CARE IN IGNITING AS THIS
MATERIAL IS HIGHLY FLAMMABLE. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGUL ATIONS.

Toxicological Information:IRRIT DATA: EYE-HMN 400 PPM. JIHTAB
25,282,1943. TOX DATA: ORL-RAT LD50: 5620 MG/KG. YKYUA6
32,1241,1981. IHL-RAT LC50: 200 GM/M3, 36 (104), 10, 1989. SRTCAC.
ORL-MUS LD50: 4100 MG/KG. GISAA 48(4),66, 1983. IHL-MUS LC50: 45
GM/M3/2H. 85GMAT -,65,1982. IPR-MUS LD50: 709 MG/KG. SCCUR*
-,5,1961. SCU-CAT LD50:3 GM/KG. AGGHAR 5,1,1933. ORL-RBT LD50:4935
MG/KG. IMSUAI 41,31,1972. SKN-RBT LD50:>20 ML/KG. UCDS**
10/4/1968. ORL-GPG LD50:5500 MG/KG. GISAAA 48(4),66,1983. SCU-GPG
LD50:3 G/MKG. AGGHAR 5,1,1933. TARGET ORGAN DATA: SENSE ORGANS &
SPEC (OTHER OLFACTION EFTS) (SUPDAT)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE. --STATE REG INFO: (1400 MG/M3) JAN
1993. OEL-GERMANY: TWA 400 PPM (1400 MG/M3) JAN 1993. OEL-HUNGARY:
TWA 400 MG/M3; STEL 1200 MG/M3 JAN 1993. OEL-JAPAN: TWA 400 PPM
(1400 MG/M 3) JAN 1993. OEL-THE NETHERLANDS: TWA 400 PPM (1400
MG/M3) JAN 1993. OEL-THE PHILIPPINES: TWA 400 PPM (1400 MG/M3) JAN
1993.OEL-POLAND: TWA 200 PPM JAN 1993. OEL-RUSSIA: TWA 400 PPM;
STEL 200 MG/M3 JA N 1993. OEL-SWEDEN: TWA 150 PPM (500 MG/M3); STEL
300 PPM (1100 MG/M3) JAN 1993. OEL-SWITZERLAND: TWA 400 PPM (1400
MG/M3); STEL 800 PPM JAN 1993. OEL-TURKEY: TWA 400 PPM (1400 MG/M3)
JAN 1993. OEL-UN ITED KINGDOM: TWA 400 PPM (OTHER INFO)

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

SARA Title III Information:N/P --ECOL INFO: (1400 MG/M3) JAN 1993. OEL
IN BULGARIA, COLOMBIA, JORDAN, KOREA, NEW ZEALAND, SINGAPORE,
VIETNAM CHECK ACGIH TLV. NIOSH REL TO ETHYL ACETATE-AIR: 10H TWA
400 PPM NIOSH* DHHS #92-100, 1992. NOHS 1974: HZD 31470; NIS 234;
TNF 37072; NOS 152; TNE 407816. NOES 1983: HZD 31470; NIS 234; TNF
40728; NOS 154; TNE 504448; TFE 119505. EPA GENETOX PROGRAM 1988,
INCONCLUSIVE: B SUBTILIS REC A SSAY. EPA TSCA SECTION 8 (B) CHEM
INVENTORY. EPA TSCA SECTION *(D) UNPUBLISHED HLTH/SFTY STUDIES ON
EPA IRIS DATABASE. EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE,
DECEMBER 1998. NIOSH ANALYTICAL METH , 1994: ETHYL ACETATE,
1457.(OTHER INFO)
Federal Regulatory Information:EUROPEAN INFO: EC INDEX NO:
607-022-00-5. HIGHLY FLAMM. IRRITANT. 4 11. HIGHLY FLAMM. S 16.
KEEP AWAY FROM SOURCES OF IGNIT - NO SMOKING. S 23. DO NOT BREATHE
VAPOR. S 29. DO NOT EMPTY INTO DRAINS. S 33. TAKE PRECAUTIONARY
MEASURES AGAINST STATIC DISCHARGES. REVIEW STDS, AND REGS. OEL=MAK.
ACGIH TLV-NOT CLASSIFIABLE AS HUMAN CARCINOGEN DTLVS* TLV/BEI,
1997. ACGIH TLV-TWA 1440 MG/M3 (400 PPM) DTLVS * TLV/BEI, 1997. EPA
FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC 54, 7740 , 1989. MSHA STD-AIR:TWA 400 PPM (1400 MG/M3).
DTLVS* 3,102,1971. (STATE REGULATORY)
State Regulatory Information:N/P. --FED REGULATORY INFO: OSHA PEL (GEN
INDU): 8H TWA 400 PPM (1400 MG/M3). CFRGBR 29,1910.1000,1994. OSHA
PEL (CONSTRUC);8HR TWA 400 PPM (1400 MG/M3). CFRGBR
29,1926.55,1994. OSHA PEL (SHIPYARD):8H TWA 400 PPM (1400 MG/M3).
CFRGBR 29,1915.1000,1993. OSHA PEL (FED CONT): (FED CONT):8H TWA
400 PPM (1400 MG/M3). CFRGBR 41,50-204.50,1994. OEL-AUSTRALIA:TWA
400 PPM (1400 MG/M3) JAN 1993. OEL-BELGIUM :TWA 400 PPM (1440
MG/M3) JAN 1993. OEL-DENMARK:TWA 300 PPM (1100 MG/M3) JAN 1993.
OEL-FINLAND:TWA 3 00 PPM (1100 MG/M3);STEL 500 PPM (1800 MG/M3) JAN
1993. OEL-FRANCE: TWA 400 PPM (ECOL INFO)