Product ID:TRIS-CHL 1M PH 7.5, 351-006-060
MSDS Date:05/25/1999
FSC:6810
NIIN:00N092855
Status Code:A
MSDS Number: CJVBB

QUALITY BIOLOGICAL, INC

7581 LINDBERG DRIVE
GAITHERSBURG, MD 20879
US

Emergency Phone: 800-443-9331

Info Phone: 301-840-9331

Cage: 0PXC7

QUALITY BIOLOGICAL, INC

GAITHERSBURG, MD 20879 US

Telephone: 301-840-9331

Cage: 0PXC7

1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-; (TRIS BASE)

CAS: 77-86-1

RTECS: TY2900000

OSHA PEL N/K

ACGIH TLV: N/K

HYDROCHLORIC ACID

CAS: 7647-01-0

RTECS: MW4025000

OSHA PEL C7 MG/M3;C5 PPM

ACGIH TLV: N/K

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

WATER

CAS: 7732-18-5

RTECS: ZC0110000

OSHA PEL N/K

ACGIH TLV: N/K

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:THE TOXICOLOGICAL PROPERTIES OF THIS
PRODUCT HAVE NOT BEEN DETERMINED. THE SOLUTION MAY CAUSE ACUTE OR
CHRONIC IRRITATION OF SKIN, EYES AND MUCOUS MEMBRANES.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:INGESTION: REPEATEDLY RINSE MOUTH WITH WATER. DRINK LARGE
QUANTITIES OF WATER. GET MEDICAL ATTENTION IF IRRITATION PERSISTS.
SKIN: IMMEDIATELY WASH SKIN WITH SOAP AND FLUSH WITH LARGE AMOUNTS
OF WATER FOR AT LEAST 15 MINUTES. GET MEDICAL ATTENTION IF CONTACT
AREA REMAINS IRRITATED. EYES: IMMEDIATELY FLUSH EYES WITH LARGE
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. GET MEDICAL ATTENTION IF
EYES REMAI N IRRITATED. INHALATION: REMOVE TO FRESH AIR. SUPPORT
BREATHING (GIVE OXYGEN OR ARTIFICIAL RESPIRATION) . EMERGENCY
EXPOSURE INFORMATION: 1-800-424-8802 (NATIONAL RESPONSE CENTER).

Extinguishing Media:USE EXTINGUISHING MEDIA APPROPRIATE TO SURROUNDING
FIRE CONDITIONS.
Fire Fighting Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:MAY EMIT TOXIC FUMES OF CARBON MONOXIDE,
CARBON DIOXIDE, AND NITROGEN OXIDES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR PROTECTIVE CLOTHING AND SAFETY GLASSES
WHILE CLEANING UP THE SPILL. MINIMIZE SPREAD OF LIQUID USING
APPROPRIATE ABSORBENT MATERIAL. PLACE IN CLOSED CONTAINERS FOR
DISPOSAL.

Handling and Storage Precautions:STORE IN TIGHTLY CLOSED CONTAINER AT
ROOM TEMPERATURE. MAY CAUSE EYE AND SKIN IRRITATION. DURING USE,
AVOID CONTACT WITH EYES, SKIN AND CLOTHING. WHEN NOT IN USE, KEEP
IN TIGHTLY CLOSED CONTAINER.
Other Precautions:THIS PRODUCT IS FOR RESEARCH USE ONLY. THIS PRODUCT
HAS NOT BEEN APPROVED FOR DIAGNOSTIC OR THERAPEUTIC USE.

Respiratory Protection:USE NIOSH APPROVED RESPIRATOR APPROPRIATE FOR
EXPOSURE OF CONCERN .
Protective Gloves:WEAR PROPER GLOVES. WEAR IMPERVIOUS GLOVES .
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYEWASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA . WEAR LAB COAT.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
WEIGHT/VOLUME: TRIS BASE: 121.14 G/L; HYDROCHLORIC ACID: 64.0 G/L;
WATER: NOT APPLICABLE.

pH:7.5 +/- 0.1
Appearance and Odor:CLEAR, COLORLESS LIQUID; ODORLESS.

Stability Indicator/Materials to Avoid:YES

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH ALL APPLICABLE
FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.

Toxicological Information:THE TOXICOLOGICAL PROPERTIES OF THIS PRODUCT
HAVE NOT BEEN DETERMINED.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

SARA Title III Information:OTHER INFORMATION: OEL-SWITZERLAND: TWA 400
PPM (980 MG/M3); STEL 800 PPM (1960 MG/M3) JANUARY 1993.
OEL-TURKEY: TWA 200 PPM (500 MG/M3) JANUARY 1993. OEL-UNITED
KINGDOM: TWA 400 PPM (980 MG/M3); STEL 500 PPM (1225 MG/M3); SKIN
JANUARY 1993. OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA, NEW
ZEALAND, SINGAPORE, VIETNAM, CHECK ACGIH TLV. NIOSH REL TO
ISOPROPYL ALCOHOL-AIR: 10H TWA 400 PPM; STEL 500 PPM NIOSH DHHS
#92-100, 92. NOHS 1974: HZD 40989; NIS 465; TNF 213605; NOS 252;
TNE 3183554. NOES 1983: HZD 40987; NIS 449; TNF 182-402; NOS 278;
TNE 4665524; TFE 2058264. (STATE REGULATIONS)
Federal Regulatory Information:FLAMMABLE LIQUID (USA DEFINITION),
FLAMMABLE, R 10 (EUROPEAN DEFINITION) (ISOPROPANOL). ACGIH TLV-TWA
400 PPM; STEL 500 PPM 85INA8 5, 337, 86. IARC CANCER REVIEW: ANIMAL
INADEQUATE EVIDENCE IMEMDT 15, 223, 77. IARC CANCER REVIEW: HUMAN
INADEQUATE EVIDENCE IMSUDL 7, 229, 87. IARC CANCER REVIEW: GROUP 3
IMSUDL 7, 229, 87. EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION
OR RE-REGISTRATION FEREAC 54, 7740, 89. MSHA STANDARD-AIR: TWA 400
PPM (980 MG/M3) DTLVS 3, 141, 71.OSHA PEL: 8H TWA 400 PPM (980
MG/M3) FEREAC 54, 2923, 89. OSHA PEL FINAL: 8H TWA 400 PPM (980
MG/M3); STEL 500 PPM (1225 MG/M3) FEREAC 54, 2923, 89. (OTHER
INFORMATION)
State Regulatory Information:SARA REGULATIONS: EPA GENETOX PROGRAM
1988, NEGATIVE: CELL TRANSFORMATION -SA7/SHE; N CRASSA-ANEUPLOIDY.
EPA TSCA CHEMICAL INVENTORY, JUNE 1990. EPA TSCA SECTION 8 (E)
STATUS REPORT 8EHQ-1180-0371. EP A TSCA SECTION 8 (E) STATUS REPORT
8EHQ-0985-0566. EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE,
JANUARY 1993. NIOSH ANALYTICAL METHODS: SEE ALCOHOLS 1, 1400.