Product ID:MAST CELL DEGRANULATING PEPTIDE, M7015
MSDS Date:01/01/1999
FSC:6505
NIIN:00N092664
Status Code:A
MSDS Number: CJVMJ

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

MAST CELL DEGRANULATING PEPTIDE

CAS: 32908-73-9

RTECS: OQ5980000

OSHA PEL N/K

ACGIH TLV: N/K

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE FATAL IF ENTERS
BLOODSTREAM. FAST ACTING. MAY BE HARMFUL BY INHALATION, INGESTION,
OR SKIN ABSORPTION. MAY CAUSE IRRITATION. PROLONGED OR REPEATED
EXPOSURE MAY CAUSE ALLERGIC REACTIONS I N CERTAIN SENSITIVE
INDIVIDUALS. A POTENT HISTAMINE-RELEASER. BIOACTIVE PEPTIDE. THE
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:IN CASE OF EXPOSURE, OBTAIN MEDICAL ATTENTION IMMEDIATELY.
INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN. SKIN: FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT
LEAST 1 5 MINUTES. REMOVE CONTAMINATED CLOTHING AND SHOES. CALL A
PHYSICIAN. INHALATION: REMOVE TO FRESH AIR. IF BREATHING BECOMES
DIFFICULT, CALL A PHYSICIAN. EYES: FLUSH WITH COPIOUS AMOUNTS OF
WATER FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING BY
SEPARATING THE EYELIDS WITH FINGERS. CALL A PHYSICIAN. NOTES TO
PHYSICIAN: NO KNOWN ANTIDOTE.

Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE EQUIPMENT .

Spill Release Procedures:WEAR NIOSH APPROVED SCBA, RUBBER BOOTS & HEAVY
RUBBER GLOVES. TREAT SPILL AREA W/A SOLUTION OF 0.1% (W/V)
PANCREATIN/OTHER CRUDE PROTEASE IN A 0.1% (W/V) SODIUM BICARBONATE
IN WATER. ALLOW TO STAND AT LEAST 2 HOURS. COMBINE MATERIAL
W/COMMERCIAL BLEACH, ABSORB ON SAND/VERMICULITE & PLACE IN A CLOSED
CONTAINER FOR DISPOSAL. WASH SPILL SITE W/COMMERCIAL BLEACH
FOLLOWED BY WATER.

Handling and Storage Precautions:CONTAINER SHOULD BE OPENED ONLY BY A
TECHNICALLY-QUALIFIED PERSON.

Respiratory Protection:NIOSH-APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:COMPATIBLE CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EMERGENCY EYEWASH AND DELUGE
SHOWER .
Supplemental Safety and Health
INGREDIENT INFORMATION: MF: C*10H*192N*40O*24S*4

Appearance and Odor:SOLID.

Stability Indicator/Materials to Avoid:YES

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:RTECS NUMBER: OQ5980000 - MCD PEPTIDE.
TOXICITY DATA: IPR-MUS LD50: 125 MG/KG; TOXIA6 22, 308, 1984.
ICE-MUS LD50: 6800 NG/KG; TOXIA6 22, 308, 1984. ADDITIONAL
INFORMATION: INTRACEREBROVENTRICULAR-MUS LD: APPROXIMATELY 10
UG/KG J. BIOL. CHEM. 259, 13957, 1984. ONLY SELECTED REGISTRY OF
TOXIC EFFECTS OF CHEMICAL SUBTANCES (RTECS) DATA IS PRESENTED HERE.
SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORM ATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:EUROPEAN INFORMATION: CAUTION: SUBSTANCE
NOT YET FULLY TESTED.
State Regulatory Information: