Product ID:N-BUTANOL MOLECULAR BIOLOGY REAGENT, B7906
MSDS Date:01/01/1999
FSC:6505
NIIN:00N092672
Status Code:A
MSDS Number: CJVPK

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

(ORAL, RAT) 790 MG/KG

CAS: 71-36-3

RTECS: EO1400000

OSHA PEL 300 MG/M3;100 PPM

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

LD50 LC50 Mixture:SEE INGREDIENT & TOXICOLOGICAL INFO
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE EFFECTS: HARMFUL IF SWALLOWED,
INHALED OR ABSORBED THROUGH SKIN. CAUSES SEVERE IRRITATION. HIGH
CONCENTRATIONS ARE EXTREMELY DESTRUCTIVE TO TISSUES OF THE MUCOUS
MEMBRANES AND UPPER RESPIRATORY TRACT, EYES AND SKIN. SYMPTOMS OF
EXPOSURE MAY INCLUDE BURNING SENSATION, COUGHING, WHEEZING,
LARYNGITIS, SHORTNESS OF BREATH, HEADACHE, NAUSEA AND VOMITING. CAN
CAUSE CNS DEPRESSION. EXPOSURE CAN CAU SE: GASTROINTESTINAL
DISTURBANCES. TARGET ORGANS: CENTRAL NERVOUS SYSTEM, EARS, LIVER,
KIDNEYS, BLOOD.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:EYES: IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING
OF THE EYES BY SEPARATING THE EYELIDS WITH FINGERS. SKIN: IN CASE
OF CO NTACT, IMMEDIATELY FLUSH SKIN WITH COPIOUS AMOUNTS OF WATER
FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING AND
SHOES. INHALATION: REMOVE TO FRESH AIR. IF NOT BREATHING GIVE
ARTIFICIAL RE SPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
INGESTION: IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON
IS CONSCIOUS. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE
REUSE.

Flash Point:=35.C, 95.F
Autoignition Temp:=342.8C, 649.F
Lower Limits:1.4%
Upper Limits:11.2%
Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE
FOAM. WATER MAY BE INEFFECTIVE FOR COOLING, BUT MAY NOT EFFECT
EXTINGUISHMENT.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT TO PREVENT CONTACT WITH SKIN AND EYES. USE WATER SPRAY
TO COOL FIRE-EXPOSED CONTAINERS. FLAMMABLE LIQUID.
Unusual Fire/Explosion Hazard:VAPOR MAY TRAVEL CONSIDERABLE DISTANCE TO
SOURCE OF IGNITION AND FLASH BACK. CONTAINER EXPLOSION MAY OCCUR
UNDER FIRE CONDITIONS.

Spill Release Procedures:EVACUATE AREA. SHUT OFF ALL SOURCES OF
IGNITION. WEAR NIOSH APPROVED SELF-CONTAINED BREATHING APPARATUS,
RUBBER BOOTS AND HEAVY RUBBER GLOVES. COVER WITH AN ACTIVATED
CARBON ABSORBENT, TAKE UP AND PLA CE IN CLOSED CONTAINERS.
TRANSPORT OUTDOORS. VENTILATE AREA AND WASH SPILL SITE AFTER
MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:KEEP TIGHTLY CLOSED. KEEP AWAY FROM
HEAT, SPARKS AND OPEN FLAME. STORE IN A COOL, DRY PLACE.
Other Precautions:DO NOT BREATHE VAPOR. AVOID CONTACT WITH EYES, SKIN
AND CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE. WASH THOROUGHLY
AFTER HANDLING. HARMFUL LIQUID. SEVERE IRRITANT.

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH AND DELUGE SHOWER .
WEAR OTHER PROTECTIVE CLOTHING. FACESHIELD (8-INCH MINIMUM).
Supplemental Safety and Health
INGREDIENT INFORMATION: MF: C*4H*10O. EC NO: 200-751-6.

Boiling Pt:=117.7C, 243.9F
Melt/Freeze Pt:=-90.C, -130.F
Vapor Pres:4 MM 20C
Vapor Density:2.55
Spec Gravity:0.810
Appearance and Odor:COLORLESS LIQUID.

ACID CHLORIDES, ACID ANHYDRIDES, OXIDIZING AGENTS, REDUCING AGENTS,
COPPER, COPPER ALLOYS, ALUMINUM, ALKALI METALS.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE.

Waste Disposal Methods:BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER BUT EXERT EXTRA CARE IN IGNITING AS THIS
MATERIAL IS HIGHLY FLAMMABLE. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGUL ATIONS. RCRA WASTE NUMBER U031.

Toxicological Information:RTECS #: EO1400000 BUTYL ALCOHOL. IRRITATION
DATA: EYE-HMN 50 PPM JIHTAB 25,282,1943. SKN-RBT 405 MG/24H MOD
BIOFX 2-15/1969. SKN-RBT 20 MG/24H MOD 85JCAE -,193,1986. EYE-RBT 2
MG SEV AJOPAA 29,1363,1 946. EYE-RBT 2 MG/24H SEV 85JCAE
-,193,1986. TOXICITY DATA: ORL-RAT LD50: 790 MG/KG SAMJAF
43,795,1969. IHL-RAT LC50:800 PPM/4H NPIRI 1,10,1974. IPR-RAT LD50:
1122 MG/KG EVHPAZ 61,321,1985. IVN-RAT LD 50: 310 MG/KG EVHPAZ
61,321,1985. ORL-MUS LD50: 2680 MG/KG GTPZAB 25(11),57,1981.
IPR-MUS LD50:254 MG/KG RCOCB8 26,75,1979. SCU-MUS LD50: 3200 MG/KG
TXAPA9 18,185,1971. IVN-MUS LD50: 377 MG/KG AIPTAK 135,330,1962.
(OTHER INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE. --OTHER INFO: (OTHER CHANGES).
GASTROINTESTINAL (OTHER CHANGES). LIVER (FATTY LIVER DEGENERATION).
LIVER (OTHER CHANGES). KIDNEY, URETER, BLADDER (OTHER CHANGES).
BLOOD (HEMORR HAGE). BLOOD (OTHER CHANGES). ONLY SELECTED REGISTRY
OF TOXIC EFFECTS OF CHEMICAL SUSBTANCES (RTECS) DATA IS PRESENTED
HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFO. --FED REG INFO: OEL-AUSTRALIA: TWA 50 PPM (150 MG/M3); SKIN
JAN 1993. OEL-AUSTRIA: TWA 100 PPM (300 MG/M3) JAN 1993.
OEL-BELGIUM: STEL 50 PPM (1 52 MG/M3); SKIN JAN 1993.
OEL-DENMARK:STEL 50 PPM (150 MG/M3); SKIN JAN 1993. OEL-FINLAND:
TWA 50 PPM (150 MG/M3); STEL 75 PPM (225 MG/M3); SKIN JAN 1993.
OEL-FRANCE: STEL 50 PPM (150 MG/M3) JAN 1993. OEL-GERMANY: TWA 100
PPM (300 MG/M3) JAN 1993. OEL-HUNGARY: TWA 100 MG/M3; STEL 200
MG/M3; SKIN JAN 1993. OEL-INDIA: TWA 50 PPM (150 MG/M3); SKIN JAN
1993. OEL-JAPAN: STEL 50 PPM (150 MG/M3); SKIN JA N 1993. OEL-THE
(SARA REG INFO)

SARA Title III Information:THIS PRODUCT IS SUBJECT TO SARA SECTION 313
REPORTING REQUIREMENTS. --TRANSPORT INFO: NETHERLANDS: TWA 50 PPM
(150 MG/M3); SKIN JAN 1993. OEL-THE PHILIPPINES: TWA 100 PPM (300
MG/M3) JAN 1993. OEL-RUS SIA: STEL 50 PPM (10 MG/M3) JAN 1993.
OEL-SWEDEN:TWA 15 PPM (45 MG/M3); STEL 30 PPM (90 MG/M3); SKIN JAN
1993. OEL-SWITZERLAND: TWA 50 PPM (150 MG/M3); STEL 100 PPM; SKIN
JAN 1993. OEL-TURKEY: TWA 100 PPM (300 MG/M3) JAN 1993. OEL-UNITED
KINGDOM:TWA 50 PPM (150 MG/M3); STEL 50 PPM; SKIN JAN 1993. OEL IN
BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV. OEL IN NEW
ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV. (SARA REG INFO)
Federal Regulatory Information:EUROPEAN INFO - EC INDEX NO:
603-004-00-6. FLAMMABLE. HARMFUL. R 10 FLAMMABLE. R 20 HARMFUL BY
INHAL. S 16 KEEP AWAY FROM SOURCES OF IGNITION - NO SMOKING.
REVIEWS, STANDARDS & REGS: OEL=MAK. ACGIH TL V-CL 152 MG/M3 (50 PPM
) (SKIN) DTLVS TLV/BEI, 1997. MSHA STANDARD-AIR: TWA 100 PPM (300
MG/M3) DTLVS 3,31,1971. OSHA PEL (GEN INDU): 8H TWA 100 PPM (300
MG/M3) CFRGBR 29,1910.1000,1994. OSHA PEL (CON STRUC): 8H TWA 100
PPM (300 MG/M3) CFRGBR 29,1926.55,1994. OSHA PEL (SHIPYARD): 8H TWA
100 PPM (300 MG/M3) CFRGBR 29,1915.1000,1994. OSHA PEL (FED CONT):
8H TWA 100 PPM (300 MG/M3) CFRGBR 41,50-204.50,1994. (TRANSPORT
INFO)
State Regulatory Information:N/P. --SARA REGS: NIOSH REL TO N-BUTYL
ALCOHOL-AIR: CL 50 PPM (SK) NIOSH DHHS #92-100,1992. NOHS 1974: HZD
13850; NIS 306; TNF 60975; NOS 160; TNE 678026. NOES 1983: HZD
13850; NIS 304; TNF 57416; NOS 179; TNE 1059965; TFE 269422. EPA
GENETOX PROGRAM 1988, NEGATIVE: HISTIDINE REVERSION-AMES TEST; IN
VITRO SCE-NONHUMAN. EPA TSCA SECTION 8(B) CHEMICAL INVENTORY. EPA
TSCA SECTION 8(D) UNPUBLISHED HEA LTH/SAFETY STUDIES ON EPA IRIS
DATABASE. EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1988.
NIO SH ANALYTICAL METHOD, 1994: ALCOHOLS II, 1401. NIOSH ANLAYTICAL
METHOD, 1996: VOLATILE ORGANIC COMPOUND, 2549.