Product ID:L-TYROSINE PLANT CELL CULTURE TESTED, T1655
MSDS Date:01/01/1999
FSC:6810
NIIN:00N093247
Status Code:A
MSDS Number: CJWLS

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

L-TYROSINE

CAS: 60-18-4

RTECS: YP2275600

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE EFFECTS: MAY BE HARMFUL BY
INHALATION, INGESTION OR SKIN ABSORPTION. CAUSES EYE AND SKIN
IRRITATION. MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT. TO THE BEST OF OUR KN OWLEDGE, THE CHEMICAL,
PHYSICAL AND TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY
INVESTIGATED. ALSO, SEE TOXICOLOGICAL INFORMATION.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:EYES: IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. SKIN: IN CASE OF CONTACT,
IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER.
INHALATI ON: IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE
ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
INGESTION: IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON
IS CONSCIO US. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE
REUSE.

Extinguishing Media:WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT TO PREVENT CONTACT WITH EYES AND SKIN.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR NIOSH APPROVED RESPIRATOR, CHEMICAL
SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP,
PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL S ITE AFTER MATERIAL PICKUP IS
COMPLETE.

Handling and Storage Precautions:DO NOT BREATHE DUST. AVOID CONTACT
WITH EYES, SKIN AND CLOTHING. WASH THOROUGHLY AFTER HANDLING. KEEP
TIGHTLY CLOSED. STORE IN A COOL, DRY PLACE.

Respiratory Protection:NIOSH APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:COMPATIBLE CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA .
Supplemental Safety and Health
PHYSICAL DATA: SOLUBILITY: ETHANOL-INSOLUBLE; ETHER-INSOLUBLE;
ACETONE-INSOLUBLE.

Melt/Freeze Pt:>300.C, 572.F
M.P/F.P Text:DEC
Solubility in Water:SLIGHTLY SOLUBLE
Appearance and Odor:WHITE POWDER.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Hazardous Decomposition Products:THERMAL DECOMPOSITION MAY PRODUCE
CARBON MONOXIDE, CARBON DIOXIDE AND NITROGEN OXIDES.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:RTECS #: YP2275600. TYROSINE, L-. TOXICITY
DATA: IPR-MUS LD50: >1450 MG/KG YKKZAJ 97,1117,1977. TARGET ORGAN
DATA: MATERIAL EFFECTS (OVARIES, FALLOPIAN TUBES). ONLY SELECTED
REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS
PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:EUROPEAN INFORMATION - IRRITANT. R
36/37/38 IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. S 26 IN
CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF WATER
AND SEEK MEDICAL ADVICE. S 36 WEA R SUITABLE PROTECTIVE CLOTHING.
REVIEWS, STANDARDS AND REGULATIONS - OEL=MAK. NOHS 1974: HZD 81869;
NIS 2; TNF 133; NOS 4; TNE 1421. NOES 1983: HZD 81869; NIS 3; TNF
275; NOS 12; TNE 14731; TFE 12371. EPA TSCA SECTION 8(B) CHEMICAL
INVENTORY.