Product ID:MEFENAMIC ACID, M4267
MSDS Date:01/01/1999
FSC:6505
NIIN:00N093128
Status Code:A
MSDS Number: CJXLC

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

ANTHRANILIC ACID, N-(2,3-XYLYL)-; (MEFENAMIC ACID).

CAS: 61-68-7

RTECS: CB4550000

LD50 LC50 Mixture:SEE INGREDIENTS & TOXICOLOGICAL INFO.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: HARMFUL IF SWALLOWED, INHALED
OR ABSORBED THROUGH SKIN. MAY CAUSE IRRITATION. MAY CAUSE NERVOUS
SYSTEM DISTURBANCES. EXPOSURE CAN CAUSE: GASTROINTESTINAL
DISTURBANCES; BLOOD EFFECTS. CHRONIC: P OSSIBLE TERATOGEN. MAY
CAUSE REPRODUCTIVE DISORDERS. TARGET ORGAN(S): KIDNEYS. TARGET
ORGAN DATA: PERIPHERAL NERVE AND SENSATION (FLACCID PARALYSIS
WITHOUT ANESTHESIA). SENSE ORGANS AND SPECIAL SENSES (MYDRIASIS).
BEHAVIORAL (ALTERED SLEEP TIME; SOMNOLENCE; TOXIC PSYCHOSIS;
CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD; ATAXIA; WITHDRAWAL).
LUNGS, THORAX OR RESPIRATION (RESPIRATORY STIMULATION). GAST
ROINTESTINAL (CHANGES (EFTS OF OVEREXP)
Effects of Overexposure:HLTH HAZ: IN STRUCTURE OR FUNCTION OF EXOCRINE
PANCREAS; ULCERATION OR BLEEDING FROM LARGE INTESTINE;
HYPERMOTILITY, DIARRHEA). LIVER (LIVER FUNCTION TESTS IMPAIRED).
KIDNEY, URETER, BLADDER (CHANGES IN TUBULES). BLOOD (OTHER
HEMOLYSIS WITH OR WITHOUT ANEMIA). SKIN AND APPENDAGES (AFTER
SYSTEMIC EXPOSURE: DERMATITIS, OTHER). MATERNAL EFFECTS (MENSTRUAL
CYCLE CHANGES OR DISORDERS). SPECIFIC DEVELOP MENTAL ABNORMALITIES
(CRANIOFACIAL; CARDIOVASCULAR SYSTEM). NUTRITIONAL AND GROSS
METABOLIC (CHANGES IN: K; BODY TEMPERATURE INCREASE; OTHER
CHANGES). TUMORIGENIC (ACTIVE AS ANTI-CANCER AGENT).

First Aid:INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS
CONSCIOUS. CALL MD. SKIN: FLUSH WITH COPIOUS AMOUNTS OF WATER FOR
AT LEAST 15 MINUTES. REMOVE CONTAMINATED CLOTHING AND SHOES. CALL
MD. INHALATI ON: REMOVE TO FRESH AIR. IF BREATHING BECOMES
DIFFICULT, CALL MD. EYES: FLUSH WITH COPIOUS AMOUNTS OF WATER FOR
AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING THE
EYELIDS WITH FINGERS. CA LL MD.

Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE
FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR NIOSH APPROVED RESPIRATOR, CHEMICAL
SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP,
PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL S ITE AFTER MATERIAL PICKUP IS
COMPLETE.

Handling and Storage Precautions:HARMFUL. HARMFUL BY INHALATION, IN
CONTACT WITH SKIN AND IF SWALLOWED. DO NOT BREATHE DUST.
Other Precautions:POSSIBLE RISK OF IRREVERSIBLE EFFECTS. POSSIBLE
TERATOGEN. REPRODUCTIVE HAZARD. NEUROLOGICAL HAZARD.

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EMERGENCY EYE WASH AND DELUGE
SHOWER . WEAR SUITABLE OTHER PROTECTIVE CLOTHING.
Supplemental Safety and Health
MFR'S INFORMATION ON INGREDIENTS: MF: C15H15NO2. EC NO: 200-513-1. --
PHYSICAL AND CHEMICAL PROPERTIES: SOLUBILITY: IN AMMONIUM -
SOLUBLE.

Solubility in Water:SUPP DATA
Appearance and Odor:SOLID.

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE, NITROGEN OXIDES.
Conditions to Avoid Polymerization:WILL NOT OCCUR.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:TOXICITY DATA: LDLO:(ORAL,WMN) 280 MG/KG/2W-I
- DRSAEA 6,230,1991. LD50:(ORAL,RAT) 740 MG/KG - TOIZAG 28,99,1981.
LD50:(IPR,RAT) 327 MG/KG - TXAPA9 18,185,1971. LD50:(IVN,RAT) 112
MG/KG; LD50:(IVN,CAT ) 100 MG/KG - CMROCX 4,17,1976.
LD50:(ORAL,MUS) 525 MG/KG. - JNPHAG 2,259,1971. LD50:(IPR,MUS) 120
MG/KG - ARZNAD 19,36,1969. LD50:(IVN,MUS) 96 MG/KG - YKKZAJ
89,1392,1969. LD50:(IMS,MUS) 400 MG/KG - PCJOAU 17,353,1983. ONLY
SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS)
DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE
INFORMATION.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:EUROPEAN INFORMATION: HARMFUL; R
20/21/22 - HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF
SWALLOWED. R 40 - POSSIBLE RISK OF IRREVERSIBLE EFFECTS. S 22 - DO
NOT BREATHE DUST. S 36 - WEAR SUITABLE PROTECTIVE CLOTHING.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.