Product ID:DL-TRYPTOPHAN CELL CULTURE TESTED T7425
MSDS Date:01/01/1999
FSC:6550
NIIN:00N093193
Status Code:A
MSDS Number: CJXNZ

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

DL-TRYPTOPHAN CELL CULTURE TESTED

CAS: 54-12-6

RTECS: YN6129200

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE EFFECTS: MAY BE HARMFUL BY
INHALATION, INGESTION, OR SKIN ABSORPTION. MAY CAUSE EYE
IRRITATION. MAY CAUSE SKIN IRRITATION. MATERIAL MAY BE IRRITATING
TO MUCOUS MEMBRANES AND UPPER RESPIRATORY TR ACT. EXPOSURE CAN
CAUSE: NAUSEA, HEADACHE, DIZZINESS, DROWSINESS. TO BEST OF OUR
KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL PROPERTIES
HAVE NOT BEEN THOROUGHLY INVESTIGATED. ADDITIONAL INFO RMATION: THE
FOOD AND DRUG ADMINISTRATION & THE CENTER FOR DISEASE CONTROL HAVE
ESTABLISHED A LINK BETWEEN L-TRYPTOPHAN AND A SOMETIMES FATAL BLOOD
DISORDER CALLED EOSINOPHILIA-MYALGIA (EFTS OF OVEREX P)
Effects of Overexposure:HLTH HAZS: SYNDROME WHICH IS MARKED BY SEVERE
MUSCLE AND JOINT PAIN, SWELLING OF THE ARMS AND LEGS, SKIN RASH AND
SOMETIMES FEVER. IT IS CHARACTERIZED BY SEVERE EOSINOPHILLIA, A
BLOOD DISORDER IN WHIC H THE WHITE BLOOD CELLS INCREASE TO AN
ABNORMALLY HIGH LEVEL. L-TRYPTOPHAN OCCURS NATURALLY IN MANY FOODS
AND INVESTIGATION HAS NOT ESTABLISHED WHETHER IT OR AN IMPURITY
INTRODUCED DURING MANUFACTURE OR DISTRIBUTION IS THE CAUSE.

First Aid:IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. IN CASE OF CONTACT,
IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER. IF
INHALED, REMOVE T O FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IF SWALLOWED,
WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A
PHYSICIAN. WASH CONTAMIN ATED CLOTHING BEFORE REUSE.

Extinguishing Media:WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR NIOSH APPRVD RESPIRATOR, CHEMICAL SAFETY
GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN A
BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE AREA
AND WASH SPILL SIT E AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:AVOID INHALATION. AVOID CONTACT WITH
EYES, SKIN AND CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE. KEEP
TIGHTLY CLOSED. STORE IN A COOL DRY PLACE.

Respiratory Protection:NIOSH-APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:COMPATIBLE CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH & DELUGE SHOWER MEETING ANSI DESIGN
CRITERIA .
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health

Melt/Freeze Pt:>289.C, 552.2F
M.P/F.P Text:289-290 C
Decomp Temp:>289.C, 552.2F
Decomp Text:289-290C
Solubility in Water:HCL: SOLUBLE
Appearance and Odor:SOLID.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE, NITROGEN OXIDES.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:IPR-MUS LD50: >1 GM/KG. BCPCA6 15,2134,1966.
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:REVIEWS, STANDARDS, AND REGULATIONS.
OEL=MAK. NOES 1983: HZD X3905; NIS 3; TNF 559; NOS 11; TNE 6205;
TFE 3513. EPA GENETOX PROGRAM 1988, NEGATIVE: SPERM
MORPHOLOGY-HUMAN. EPA TSCA SECTION 8 (B) CHEMI CAL INVENTORY.