Product ID:CAFFEINE
MSDS Date:08/02/1995
FSC:NIIN:Submitter:D DG
Status Code:A
MSDS Number: CJZGW

Emergency Phone: 716-359-2502

Info Phone: 716-359-2502

Preparer: MICHAEL RASZEJA

Cage: EO227

Telephone: (716) 359-2502

Cage: 63759

CAFFEINE

CAS: 58-08-2

RTECS: EV6475000

LD50 LC50 Mixture:ORAL-MOUSE LD50: 127MG/KG
Health Hazards Acute and Chronic:INGESTION AND INHALATION: NO TLV
ESTABLISHED. MAY ACT AS STIMULANT IF EXCESSIVE INGESTION. LARGE
DOSES(>1G) MAY CAUSE PALPITATION,E XCITEMENT, INSOMNIA, DIZZINESS,
HEADACHE AND VOMITING. SKIN/EYES: AS DUST OR VAPOR MAY BE AN
IRRITANT. EXERCISE APPROPRIATE PROCEDURES TO MINIMIZE POTENTIAL
HAZARDS.
Effects of Overexposure:INGESTION/INHALATION: PALPITATION, EXCITEMENT,
INSOMNIA, DIZZINESS, HEADACHE AND VOMITING. SKIN/EYES: IRRITANT.
Medical Cond Aggravated by Exposure:NONE SPECIFIED

First Aid:INGESTION:I F SWALLOWED ,IF CONSCIOUS, GIVE 1-2 GLASSES OF
WATER TO DRINK, INDUCE VOMITING AND CALL PHYSICIAN. NEVER GIVE
ANYTHING BY MOUTH TO AN UNCONSCIOUS PERSON. SKIN: FLUSH WITH WATER,
THEN WASH WITH MILD SOAP AND WATER. EYES: FLUSH THOROUGHLY WITH
WATER FOR 15 MINUTES, LIFTING UPPER AND LOWER EYELIDS OCCASIONALLY.
GET MEDICAL ATTENTION. INHALATION: REMOVE TO FRESH AIR.I F ILLNESS
OR DISCOMFO RT DEVELOPS, GET MEDICAL ATTENTION.

Flash Point:=925.C, 1697.F
IGNITION TEMP
Lower Limits:2
Upper Limits:16
Extinguishing Media:USE ANY MEDIA SUITABLE FOR EXTINGUISHING SUPPORTING
FIRE.
Fire Fighting Procedures:IN FIRE CONDITIONS, WEAR A
NIOSH/MSHA-APPROVED, SELF-CONTAINED BREATHING APPARATUS AND FULL
PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard:WHEN HEATED TO DECOMPOSITION,EMITS TOXIC
FUMES OF NITROUS OXIDES AND OTHER HAZARDOUS MATERIALS; CAN REACT
VIGOROUSLY WITH OXIDIZING MATERIALS. SEVERE (BUREAU OF MINES
EXPLSOION HAZARD RATINGS) AS DUST .

Spill Release Procedures:WEAR PROTECTIVE SAFETY EQUIPMENT AND USE
ADEQUATE VENTILATION.AVOID MAKING DUST. SWEEP UP AND PLACE IN
SUITABLE CONTAINER FOR DISPOSAL. FLUSH SPILL AREA WITH WATER. DO
NOT ALLOW WATER TO POLLUTE WATER WAYS AND STREAMS. RECOVER FOR USE
IF NOT CONTAMINATED.
Neutralizing Agent:NONE SPECIFIED

Handling and Storage Precautions:STORE IN COOL, DRY PLACE. WASH
THOROUGHLY AFTER HANDLING. AVOID BREATHING DUST OR VAPOR. DO NOT
INGEST. REMOVE AND WASH CONTAMINATED CLOTHING. KEEP CONTAINER
TIGHTLY CLOSED WHEN NOT IN USE.
Other Precautions:THE FDA HAS RECENTLY PROPSED REMOVAL OF CAFFEINE FROM
ITS "GENERALLY RECOGNIZED AS SAFE" LIST AND IS GATHERING ADDITIONAL
INFORMATION. CONCERNS WITH EXCESSIVE USE INCLUDE POSSIBLE
REPRODUCTIVE EFFECTS TO FETAL CRANIOFACIAL AREA, MUCULOSKELETAL
SYSTEM, POSSIBLE BLADDER CANCER AND MIOCARDIAL INFACTION .

Respiratory Protection:NONE SHOULD BE NEEDED IN NORMAL LABORATORY
HANDLING.IF DUSTY CONDITIONS PREVAIL,WORK IN A VENTILATION HOOD OR
WEAR A NIOSH/MSHA APPROVED DUST MASK.
Ventilation:LOCAL/MECHANICAL(GENERAL):RECOMMENDED
Protective Gloves:RUBBER
Eye Protection:CHEMICAL SAFETY GLASSES
Other Protective Equipment:GOGGLES,LAB COAT,VENTILATION HOOD,PROPER
GLOVES AND EYE WASH STATION.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING. AVOID BREATHING
DUST OR VAPOR. DO NOT INGEST. REMOVE AND WASH CONTAMINATED
CLOTHING.
Supplemental Safety and Health
WARD'S P/N: 39W0865 ***OTHER PRECAUTIONS: FOR LABORATORY USE ONLY. NOT
FOR DRUG, FOOD OR HOUSEHOLD USE. KEEP OUT OF REACH OF CHILDREN.

HCC:T2
Boiling Pt:=178.C, 352.4F
Melt/Freeze Pt:=238.C, 460.4F
M.P/F.P Text:SUBLIMES AT
Vapor Pres:760
Spec Gravity:1.23
Solubility in Water:1G DISSILVES IN 46ML H20
Appearance and Odor:WHITE NEEDLES OR WHITE POWDER; NO ODOR
Percent Volatiles by Volume:0.5%

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZERS,HOT ALKALIES,CHLORINE WATER.
Stability Condition to Avoid:EXCESSIVE TEMPERATURES AND HEAT.
Hazardous Decomposition Products:WHEN HEATED TO DECOMPOSITION, EMITS
TOXIC FUMES OF NITROUS OXIDES,CARBON MONOXIDE AND CARBON DIOXIDE.

Waste Disposal Methods:DISCHARGE, TREATMENT OR DISPOSAL MAY BE SUBJECT
TO FEDERAL,STATE OR LOCAL LAWS. THESE DISPOSAL GUIDELINES ARE
INTENDED FOR THE DISPOSAL OF CATALOG-SIZE QUANTITIES ONLY. DISPOSE
OF IN AN APPROVED INCI NERATOR.

Toxicological Information:RTECS NO. EV6475000 TOXICITY DATA: ORAL-CHILD
LDLO: 320 MG/KG ORAL-WOMAN LDLO: 1000 MG/KG, ORAL-INFANT TDLO:
14,700 UG/KG, ORAL-MOUSE LD50: 127 MG/KG.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Transport Information:D.O.T.: POISONOUS SOLIDS, N.O.S., (CAFFEINE),
6.1, UN 2811.