Product ID:ACCESS CK-MB, 2 X 50 DETERMINATIONS, 33300
MSDS Date:12/30/1994
FSC:NIIN:Submitter:N EN
Status Code:A
MSDS Number: CKTWW

SANOFI DIAGNOSTICS PASTEUR

1000 LAKE HAZELTINE DR
CHASKA, MN 55318
US

Emergency Phone: 1-800-666-2111

Info Phone: 800-666-7111; 612-448-4848

Cage: 0TEN9

SANOFI DIAGNOSTICS PASTEUR

CHASKA, MN 55318 US

Telephone: 800-666-7111; 612-448-4848

Cage: 0TEN9

2-METHYL-4-ISOTHIAZOLIN-3-ONE. (MFR. INVALID CAS #

NOT AVAILABLE).

ALKALINE PHOSPHATASE.

CAS: 9001-78-9

ANIMAL SERUM (MURINE)

SODIUM AZIDE. (NAN3)

CAS: 26628-22-8

RTECS: VY8050000

EPA Report Quantity: 1000 LBS

DOT Report Quantity: 1000 LBS

ANIMAL ASCITES (MURINE).

BOVINE SERUM ALBUMIN. (BSA)

CAS: 9048-46-8

SURFACTANT TWEEN 20

CAS: 9005-64-5

RTECS: TR7400000

MISC INORGANIC SALTS. (I.E. NACL, MGCL2 AND ZNCL2)

WATER. (H2O)

CAS: 7732-18-5

RTECS: ZC0110000

TRIS HYDROXYMETHYL AMINOMETHANE. (BASE)

CAS: 77-86-1

RTECS: TY2900000

PROCLIN 300

2-CHLORO-2 METHYL-4-ISOTHIAZOLIN-3-ONE. (COMPONENT OF

CAS: 26172-55-4

RTECS: NX8156850

TRIS HYDROXYMETHYL AMINOMETHANE (BASE)

CAS: 1185-53-1

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:CAUTION! THIS MATERIAL CONTAINS
NON-STERILE ANIMAL SERUM (MURINE), ANIMAL ASCITES (MURINE), AND
BOVINE SERUM ALBUMIN (BSA). THE POTENTIAL FOR HUMAN DISEASE
TRANSMISSION EXISTS. HANDLE AS A BIOHAZARD, CLASS II (CDC/NIH
GUIDELINES). PROCLIN 300: MICROBIOCIDE PRESERVATIVE THAT IN ITS
CONCENTRATED FORM IS A CORROSIVE. AT THE CONCENTRATION OF THIS
PRODUCT, IT IS NOT CORROSIVE BUT IS AN EYE AND SKIN IRR ITANT AND
MAY BE A POTENTIAL SKIN SENSITIZER IN SUSCEPTIBLE INDIVIDUALS.
PARAMAGNETIC PARTICLES: SMALL MAGNETIC PARTICLES WITH AN OUTER
COATING OF PLASTIC. THE MAGNETIC PARTICLE IS IRON BASED. THE COA
TING IS LATEX BASED. (SIGNS OF OVEREXP)
Effects of Overexposure:HEALTH HAZARDS (CONT): THE PARTICLES ARE
CONSIDERED NORMAL MATERIALS BUT TAKE ON THE HAZARDS OF ANY PROTEINS
BOUND TO THEIR SURFACE. ALKALINE PHOSPHATASE: ENZYME THAT MAY CAUSE
IRRITATION OR ALLERGIC REACTION IN SUSCEPTIBLE INDIVIDUALS.
SYMPTOMS OF OVEREXPOSURE MAY INCLUDE: HEADACHE, CONGESTION AND EYE
IRRITATION. SKIN CONTACT MAY RESULT IN DERMATITIS. OVEREXPOSURE TO
AZIDE MAY CAUSE HEADACHES, D IZZINESS, AND FAINTING. SODIUM AZIDE:
MAY REACT WITH LEAD AND COPPER PLUMBING TO FORM HIGHLY EXPLOSIVE
METAL AZIDES. IT IS A HIGHLY POISONOUS AGENT. MAY CAUSE EYE, SKIN
AND TISSUE IRRITATION IF SPLAS HED, SPILLED ON THE BODY
(TOXICOLOGICAL)

First Aid:EYE CONTACT: WASH EYES WITH COPIOUS AMOUNTS OF WATER FOR AT
LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING THE
EYELIDS WITH FINGERS. SKIN CONTACT: REMOVE CONTAMINATED CLOTHING.
WASH AND RIN SE AFFECTED AREA(S) THOROUGHLY WITH SOAP AND WATER.
MAY CAUSE ALLERGIC SKIN REACTIONS. SWALLOWING: WASH OUT MOUTH WITH
WATER. INDUCE VOMITING. CALL A PHYSICIAN OR LOCAL POISON CONTROL
CENTER. INHALA TION: REMOVE FROM EXPOSURE AREA TO FRESH AIR.

Flash Point:NOT APPLICABLE.
Extinguishing Media:WATER, CO2, DRY CHEMICAL OR ALCOHOL FOAM.
Fire Fighting Procedures:(ANSI APPROVED, ) SELF-CONTAINED BREATHING
APPARATUS AND PROTECTIVE CLOTHING SHOULD BE WORN.
Unusual Fire/Explosion Hazard:FIRE: NOT FLAMMABLE (EXCEPT FOR PACKAGING
MATERIALS). COMBUSTION PRODUCTS: PRINCIPALLY CARBON, NITROGEN AND
SULFUR OXIDES.

Spill Release Procedures:SPILL: CLEAN UP WITH ABSORBENT MATERIAL AND
APPROPRIATE DISINFECTANT. ABSORB AND PLACE IN A SUITABLE WASTE
CONTAINER. USE UNIVERSAL PRECAUTIONS AND GOOD CLINICAL LABORATORY
PRACTICES. AVOID DIRECT CON TACT WITH THE MATERIAL BY WEARING
APPROPRIATE PERSONAL PROTECTIVE EQUIPMENT SUCH AS GLOVES,
FACESHIELD, LAB COAT, ETC.

Handling and Storage Precautions:FOLLOW PROPER LABORATORY SAFETY
GUIDELINES FOR CHEMICALS AND BIOLOGICALS. WEAR GLOVES TO PREVENTT
SKIN CONTACT. AVOID SPLASHING OR GENERATION OF AEROSOLS. WEAR
APPROPRIATE PERSONAL PROTECTIVE EQUIPME NT SUCH AS FACE SHIELD,
GLOVES, LAB COAT, ETC. HANDLE IN ACCORDANCE WITH LOCAL, (OTHER
PRECAUTIONS)
Other Precautions:HANDLING AND STORAGE PRECAUTIONS (CONT): STATE, AND
FEDERAL REGULATIONS. CONSULT WITH YOUR SAFETY AND ENVIRONMENTAL
HEALTH OFFICER. STORING: STORE AT 2C TO 10C. AVOID FREEZING
REAGENTS.

Respiratory Protection:A NIOSH APPROVED RESPIRATOR APPROPRATE FOR THE
EXPOSURE OF CONCERN .
Ventilation:NORMAL LAB VENTILATION IS ADEQUATE UNLESS AEROSOLS ARE
GENERATED. IF AEROSOLS ARE GENERATED, CONSULT WITH YOUR SAFETY AND
ENVIRONMENTAL HEALTH OFFICER.
Protective Gloves:APPROPRIATE TO PREVENT SKIN CONTACT.
Eye Protection:ANSI APPRVD SAFETY GLASSES, GOGGLES OR FACE SHIELD
W/SAFETY GLASSES OR GOGGLES.
Other Protective Equipment:LAB COAT OR GOWN TO PREVENT SKIN CONTACT.
EYEWASH & DELUGE SHOWER MEETING ANSI DESIGN CRITERIA .
Work Hygienic Practices:WASH THOROUGHLY AFTER REMOVING GLOVES.
Supplemental Safety and Health
REFER TO ASSAY MANUAL FOR PRODUCT INSERT FOR ADDITIONAL PRODUCT
INFORMATION. REAGENTS ARE A MIXTURE OF INGREDIENTS. REFER TO
CHEMICAL SPECIFIC MSDS FOR ADDITIONAL DATA.

pH:BETWEEN 5 AND 9
Solubility in Water:SOLUBLE IN WATER.
Appearance and Odor:REAGENT PACK - TRANSLUCENT SOLID CONTR W/LIQ IN
THREE OF FIVE WELLS. NO ODOR.

Stability Indicator/Materials to Avoid:YES
SODIUM AZIDE MAY REACT WITH SOME METALS (SUCH AS COPPER OR LEAD) TO
FORM POTENTIALLY EXPLOSIVE METAL AZIDES .
Hazardous Decomposition Products:COMBUSTION PRODUCTS: PRINCIPALLY
CARBON, NITROGEN AND SULFUR OXIDES.

Waste Disposal Methods:DISPOSE OF MATERIAL IN ACCORDANCE WITH LOCAL,
STATE AND FEDERAL REGULATIONS. CONTACT YOUR SAFETY AND
ENVIRONMENTAL HEALTH OFFICER FOR DISPOSAL PROCEDURES.

Toxicological Information:N/P. SIGNS AND SYMPTOMS OF OVEREXPOS
(CONT): OR INGESTED. MAY BE FATAL IF INGESTED OR INJECTED IN
QUANTITIES ABOVE THOSE FOUND IN THIS PRODUCT. TRIS HYDROXYMETHYL
AMINOMETHANE: MAY IRRITATE MUCOUS MEMBRANES AND THE UPPER
RESPIRATORY TRACT IF INHALED. ANIMAL SERUM: POTENTIALLY INFECTIOUS
MATERIAL IF SKIN IS PENETRATED AND/OR MUCOUS MEMBRANES ARE EXPOSED.
ANIMAL ASCITES: POTENTIALLY INFECTIOUS M ATERIAL IF SKIN IS
PENETRATED AND/OR MUCOUS MEMBRANES ARE EXPOSED. BOVINE SERUM
ALBUMIN: POTENTIALLY INFECTIOUS MATERIAL IF SKIN IS PENETRATED
AND/OR MUCOUS MEMBRANES ARE EXPOSED. SURFACTANT TWEEN 20:
DETERGENT (ECOLOGICAL)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:N/P. TOXICOLOGICAL (CONT): THAT CAN BE AN EYE IRRITANT.
MISC. INORGANIC SALTS: MAY CAUSE TEMPORARY EYE, SKIN, AND UPPER
RESPIRATORY TRACT IRRITATION. WATER: NOT APPLICABLE.