Product ID:METHYL SULFOXIDE
MSDS Date:11/13/1985
FSC:NIIN:Submitter:F BT
Status Code:A
MSDS Number: CLRDC

Emergency Phone: 314-539-1600

Info Phone: 314-982-5000

Cage: 1BF21

Telephone: 314-982-5000

Cage: 1BF21

METHYL SULFOXIDE

CAS: 67-68-5

RTECS: PV6210000

Health Hazards Acute and Chronic:WARNING! HARMFUL IF SWALLOWED,
INHALED OR ABSORBED THROUGH SKIN. CAUSES IRRITATION. COMBUSTIBLE.
AVOID BREATHING MIST. KEEP CONTAINER CLOSED. USE WITH ADEQUATE
VENTILATION. AVOID CONTACT WITH E YES, SKIN AND CLOTHING. WASH
THOROUGHLY AFTER HANDLING.
Effects of Overexposure:INHALATION: INHALATION OF VAPORS OR MIST MAY
IRRITATE RESPIRATORY TRACT RESULTING IN SYMPTOMS OF COUGHING OR
BURNING SENSATION. INGESTION: ABDOMINAL PAIN, VOMITING, DIARRHEA,
DROWSINESS. SKIN: AN IRRI TANT CAUSING REDNESS, ITCHING, AND
SCALING, READILY ABSORBED THROUGH THE SKIN. GARLIC-LIKE TASTE AND
ODOR MAY DEVELOP ON THE BREATH AND SKIN. TRANSIENT DISTURBANCES OF
COLOR VISION, PHOTOPHOBIA, HEADA CHE, DIARRHEA, AND DERMATITIS MAY
RESULT FROM SKIN APPLICATIONS. EYE: REDNESS, PAIN, BLURRED VISION.
Medical Cond Aggravated by Exposure:PERSONS WITH PRE-EXISTING SKIN
DISORDERS OR EYE PROBLEMS OR IMPAIRED LIVER OR KIDNEY FUNCTION MAY
BE MORE SUSCEPTIBLE TO THE EFFECTS OF THE SUBSTANCE. TOPICAL
APPLICATION ENHANCES DERMAL ABSORPTION.

First Aid:INHALATION: REMOVE TO FRESH AIR. INGESTION: IF SWALLOWED,
INDUCE VOMITING IMMEDIATELY BY GIVING TWO GLASSES OF WATER, OR MILK
IF AVAILABLE AND STICKING FINGER DOWN THROAT. NEVER GIVE ANTHING
BY MOUT H TO AN UNCONSCIOUS PERSON. EYE: WASH EYES WITH PLENTY OF
WATER FOR AT LEAST 15 MINUTES. IN ALL CASES, SEEK IMMEDIATE
MEDICAL ATTENTION!

Flash Point Method:CC
Flash Point:=88.9C, 192.F
Autoignition Temp:=215.C, 419.F
Lower Limits:2.6
Upper Limits:28.5
Extinguishing Media:DRY CHEMICAL, FOAM OR CARBON DIOXIDE.
Fire Fighting Procedures:IN THE EVENT OF A FIRE, WEAR FULL PROTECTIVE
CLOTHING AND NIOSH-APPROVED SELF-CONTAINED BREATHING APPARATUS WITH
FULL FACEPIECE OPERATED IN THE PRESSURE DEMAND OR OTHER POSITIVE
PRESSURE MODE.
Unusual Fire/Explosion Hazard:ABOVE FLASH POINT, VAPOR-AIR MIXTURES ARE
EXPLOSIVE WITHIN FLAMMABLE LIMITS.

Spill Release Procedures:VENTILATE AND EVACUATE AREA. CLEAN0UP
PERSONNEL MAY REQUIRE PROTECTIVE CLOTHING AND RESPIRATORY
PROTECTION FROM VAPORS. ALLOW ONLY QUALIFIED PERSONNEL TO HANDLE
THE SPILL. CONTAIN AND RECOVER SPILLS W HEN POSSIBLE. COVER LARGER
SPILLS WITH EARTH, SAND, OR INERT SOLID. SCOOP UP WITH NON-SPARKING
TOOLS AND PLACE IN AN APPROPRIATE CONTAINER.

Handling and Storage Precautions:KEEP IN A TIGHTLY CLOSED CONTAINER.
PROTECT FROM PHYSICAL DAMAGE. STORE IN A COOL, DRY, VENTILATED
AREA AWAY FROM SOURCES OF HEAT, MOISTURE AND INCOMPATIBILITIES.

Respiratory Protection:FOR CONDITIONS OF USE WHERE EXPOSURE TO THE
VAPOR IS APPARENT, A HALF MASK CHEMICAL CARTRIDGE RESPIRATOR MAY BE
WORN. FOR EMERGENCIES, A SELF-CONTAINED BREATHING APPARATUS MAY BE
NECESSARY.
Ventilation:A LOCAL EXHAUST SYSTEM WHICH CAPTURES THE CONTAMINANT AT
ITS SOURCE IS RECOMMENDED.
Protective Gloves:IMPERVIOUS
Eye Protection:CHEMICAL SAFETY GOGGLES
Other Protective Equipment:IMPERVIOUS PROTECTIVE CLOTHING, BOOTS, LAB
COAT, APRON OR COVERALLS. MAINTAIN EYE WASH FOUNTAIN AND
QUICK-DRENCH FACILITIES IN WORK AREA.
Supplemental Safety and Health
NFPA RATINGS: HEALTH=1, FLAMMABILITY=1, REACTIVITY=0.

Boiling Pt:=188.9C, 372.F
Melt/Freeze Pt:=18.5C, 65.3F
Vapor Pres:0.37
Vapor Density:2.7
Spec Gravity:1.10
Evaporation Rate & Reference:4.3
Solubility in Water:MISCIBLE WITH WATER.
Appearance and Odor:CLEAR, COLORLESS, ODORLESS LIQUID.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDANTS, ACYLHALIDES, ARYLHALIDES, BROMOBENZOYL ACETANILIDE,
MAGNESIUM PERCHLORATE, PERCHLORIC ACID AND SODIUM HYDROXIDE.
Hazardous Decomposition Products:UPON HEATING ABOVE 100C, SULFUR
DIOXIDE IS EVOLVED FROM THIS SUBSTANCE. HAZARDOUS THERMO-OXIDATIVE
DEGRADATION PRODUCTS FROM DMSO INCLUDE FORMALDEHYDE, METHYL
MERCAPTAN AND SULFUR DIOXIDE.

Waste Disposal Methods:WASTE MAY BE DISPOSED IN A RCRA APPROVED
FACILITY.

Toxicological Information:ORAL RAT: 17, 500 MG/KG. IRRITATION DATA:
SKIN RABBIT: 10 MG/24 HOUR, MILD EYE RABBIT: 100 MG. MUTATION
REFERENCES CITED. REPRODUCTIVE EFFECTS CITED.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

SARA Title III Information:SARA 302/313: NO. SARA 311/312: ACUTE,
CHRONIC, FIRE.
Federal Regulatory Information:CERCLA: NO RCRA: NO