Flash Point:43 F (6 C) (OC)
Autoignition Temp:975 F (524 C)
Lower Limits:3%
Upper Limits:16%
Extinguishing Media:alcohol resistant foam, carbon dioxide, regular dry
chemical, water, alcohol resistant foam Large fires: Use
alcohol-resistant foam or flood with fine water spray.
Fire Fighting Procedures:Move container from fire area if it can be
done without risk. Dike for later disposal. Do not scatter spilled
material with high-pressure water streams. Cool containers with
water spray until well after the fire is out. Stay away from the
ends of tanks. Withdraw immediately in case of rising sound from
venting safety device or any discoloration of tanks due to fire.
For tank, rail car or tank truck, evacuation radius: 800 meters
(1/2 mile). Water may be ineffective.
Unusual Fire/Explosion Hazard:Severe fire hazard. Vapor/air mixtures
are explosive. The vapor is heavier than air. Vapors or gases may
ignite at distant ignition sources and flash back.

Spill Release Procedures:Avoid heat, flames, sparks and other sources
of ignition. Do not touch spilled material. Stop leak if possible
without personal risk. Reduce vapors with water spray. Small
spills: Absorb with sand or other non-combustible material. Collect
spilled material in appropriate container for disposal. Large
spills: Dike for later disposal. Remove sources of ignition. Keep
unnecessary people away, isolate hazard area and deny entry. Notify
Local Emergency Planning Committee and State Emergency Response
Commission for release greater than or equal to RQ (U.S. SARA
Section 304). If release occurs in the U.S. and is reportable under
CERCLA Section 103, notify the National Response Center at
(800)424-8802 (USA) or (202)426-2675 (USA).
Neutralizing Agent:

Handling and Storage Precautions:Store and handle in accordance with
all current regulations and standards. Subject to storage
regulations: U.S. OSHA 29 CFR 1910.106. Protect from physical
damage. Store outside or in a detached building. Inside storage:
Store with flammable liquids. Keep separated from incompatible
substances. Grounding and bonding required. Keep separated from
incompatible substances.
Other Precautions:

Respiratory Protection:The following respirators and maximum use
concentrations are drawn from NIOSH and/or OSHA. 200 ppm Any
chemical cartridge respirator with organic vapor cartridge(s). Any
supplied-air respirator. 500 ppm Any supplied-air respirator. Any
powered, air-purifying respirator with organic vapor cartridge(s).
Any chemical cartridge respirator with a full facepiece and organic
vapor cartridge(s). Any air-purifying respirator with a full
facepiece and an organic vapor canister. Any self-contained
breathing apparatus with a full facepiece. Any supplied-air
respirator with a full facepiece. Escape - Any air-purifying
respirator with a full facepiece and an organic vapor canister. Any
appropriate escape-type, self-contained breathing apparatus. For
Unknown Concentrations or Immediately Dangerous to Life or Health -
Any supplied-air respirator with full facepiece and operated in a
pressure-demand or other positive-pressure mode in combination with
a separate escape supply. Any self-contained breathing apparatus
with a full facepiece.
Ventilation:Provide local exhaust ventilation system. Ventilation
equipment should be explosion-resistant if explosive concentrations
of material are present. Ensure compliance with applicable exposure
limits.
Protective Gloves:Wear appropriate chemical resistant gloves.
Eye Protection:Wear splash resistant safety goggles with a faceshield.
Provide an emergency eye wash fountain and quick drench shower in
the immediate work area.
Other Protective Equipment:Wear appropriate chemical resistant
clothing.
Supplemental Safety and Health
ACETONITRILE: 40 ppm (70 mg/m3) OSHA TWA 60 ppm (105 mg/m3) OSHA STEL
(vacated by 58 FR 35338, June 30, 1993) 40 ppm ACGIH TWA 60 ppm
ACGIH STEL 20 ppm (34 mg/m3) NIOSH recommended TWA 10 hour(s)

Boiling Pt:180 F (82 C)
Melt/Freeze Pt:-51 F (-46 C)
Vapor Pres:73 mmHg @ 20 C
Vapor Density:1.42
Spec Gravity:0.7857
pH:Not available
Evaporation Rate & Reference:5.79 (butyl acetate=1)
Solubility in Water:soluble
Appearance and Odor:PHYSICAL STATE:liquid COLOR:colorless ODOR:sweet
odor
Corrosion Rate:

Stability Indicator/Materials to Avoid:Stable at normal temperatures
and pressure.
Stability Condition to Avoid:Avoid heat, flames, sparks and other
sources of ignition. Minimize contact with material. Avoid
inhalation of material or combustion by-products. Keep out of water
supplies and sewers.
Hazardous Decomposition Products:Thermal decomposition products:
cyanides Thermal decomposition products: cyanides
Conditions to Avoid Polymerization:Will not polymerize.

Waste Disposal Methods:Subject to disposal regulations: U.S. EPA 40 CFR
262. Hazardous Waste Number(s): D001. Subject to disposal
regulations: U.S. EPA 40 CFR 262. Hazardous Waste Number(s): U003.
Dispose in accordance with all applicable regulations.

Toxicological Information:ACETONITRILE: IRRITATION DATA: 500 mg open
skin-rabbit mild; 100 ul/24 hour(s) eyes-rabbit moderate TOXICITY
DATA: 7551 ppm/8 hour(s) inhalation-rat LC50; >2 gm/kg skin-rabbit
LD50; 2460 mg/kg oral-rat LD50 CARCINOGEN STATUS: ACGIH: A4 -Not
Classifiable as a Human Carcinogen LOCAL EFFECTS: Irritant:
inhalation, eye ACUTE TOXICITY LEVEL: Moderately Toxic: ingestion
Slightly Toxic: inhalation TARGET ORGANS: blood MEDICAL CONDITIONS
AGGRAVATED BY EXPOSURE: central nervous system disorders, heart or
cardiovascular disorders, kidney disorders, liver disorders, skin
disorders and allergies TUMORIGENIC DATA: Available. MUTAGENIC
DATA: Available. REPRODUCTIVE EFFECTS DATA: Available.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:ECOTOXICITY DATA: FISH TOXICITY: 1000000 ug/L 96 hour(s)
LC50 (Mortality) Fathead minnow (Pimephales promelas) INVERTEBRATE
TOXICITY: 0.024-0.199 ug/L 4-72 hour(s) (Residue) Bent-nosed clam
(Macoma nasuta) ALGAL TOXICITY: 11.2 ug/L 24 hour(s) EC50
(Photosynthesis) Green algae (Selenastrum capricornutum)

Transport Information:U.S. DOT 49 CFR 172.101: PROPER SHIPPING NAME:
Acetonitrile ID NUMBER: UN1648 HAZARD CLASS OR DIVISION: 3 PACKING
GROUP: II LABELING REQUIREMENTS: Flammable liquid

SARA Title III Information: SARA TITLE III SECTION 302 EXTREMELY
HAZARDOUS SUBSTANCES (40 CFR 355.30): Not regulated. SARA TITLE
III SECTION 304 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355.40): Not
regulated. SARA TITLE III SARA SECTIONS 311/312 HAZARDOUS
CATEGORIES (40 CFR 370.21): ACUTE: Yes CHRONIC: No FIRE: Yes
REACTIVE: No SUDDEN RELEASE: No SARA TITLE III SECTION 313 (40
CFR 372.65): ACETONITRILE
Federal Regulatory Information:CERCLA SECTIONS 102a/103 HAZARDOUS
SUBSTANCES (40 CFR 302.4): ACETONITRILE: 5000LBSRQ OSHA PROCESS
SAFETY (29CFR1910.119): Not regulated.
State Regulatory Information: California Proposition 65: Not regulated.